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5-HTP 100 mg

product on market Capsule Nested Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-HTP serves as a precursor to serotonin and is researched for its role in supporting mood and sleep. There is moderate evidence suggesting its effectiveness for managing depressive symptoms. However, overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegan Capsule(s)
Serving Size
120
Servings
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Rice Flour Plant Cellulose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Take 1 vegan capsule daily with water as needed.

Warnings & Precautions

Warning: Use only as directed. Consult your healthcare professional before use if you are pregnant or nursing, have a serious medical condition, or use prescription medications.

For adult use only.

Do not use if safety seal is broken.

Allergies? We have you covered. Contains no wheat, gluten, GMO, soy, dairy, egg, corn, fish, shellfish, nuts, tree nuts, yeast, barley, or added sugar.

Formulation Notes

Our mission: To better your health & wellness with clean ingredients backed by evidence-based science. Guaranteed for life We're confident you'll love our 5-HTP, but if you don't call or email us for a full refund. Radically Transparent You deserve to know everything that goes into your body. We include every single ingredient on the label.

Third party tested Every batch is certified to ensure you get all the good stuff.

Balance the levels of serotonin to promote relaxation and better sleep habits. Balanced serotonin levels offer support during stressful times. Healthy serotonin levels may help with better sleep.

Sleep and Stress Support

Vegan

Non GMO

Allergies? We have you covered. Contains no wheat, gluten, GMO, soy, dairy, egg, corn, fish, shellfish, nuts, tree nuts, yeast, barley, or added sugar.

Gluten free

Additional Information

Nested Naturals 1% for health & happiness Your purchase helps make the world a healthier and happier place.

Third Party Tested Certified GMP Facility

Store in a cool, dry place. Avoid excessive heat.

Made with love

Lifetime Guarantee

Metadata

Product Details

UPC / SKUX000SWRIOH
DSLD Entry Date2023-06-22
Product TypeAmino acid/Protein
FormCapsule
DSLD ID286807
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.