Nugenix Nitric Oxide Booster by Nugenix — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
Limited research evidence available for ingredients

B Label Compliance Grade

Product Label

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Label Data

4 Capsule(s) Serving Size

25 Servings

Other Combinations Product Type

0% Evidence Coverage

Supplement Facts — Evidence Check

L-Citrulline

2000 mg

📊 Market median: 2000.0mg (275 products)

Median 2000.0mg This product: 2000mg

L-Arginine Alpha Ketoglutarate

500 mg

📊 Market median: 500.0mg (143 products)

This product: 500mg

50 mg

Pine bark extract

25 mg

Other Ingredients

Gelatin Dicalcium Phosphate Magnesium Stearate Silica

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (97% of products) Structure/Function (91% of products) Nutrient (29% of products) No Claim (2% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Adult Usage: Take four (4) capsules once daily, with or without food.

⚠️ Warnings & Precautions

Precautions: Only for adults over 18 years.

Use only as directed.

Consult your healthcare practitioner if you have or suspect a medical condition or if you use any medications, as extracts may alter the potency and/or side effects of certain medications.

Discontinue use two weeks prior to surgery or if any serious adverse reaction occurs. Do not use if safety seal is missing.

Keep out of the reach of children.

🧪 Formulation Notes

Powerful vasodilation enhancer Helps to: Boost N.O. production Increase muscle pumps Promote vasodilation

Additional Information

Keep product at room temperature and humidity [59 - 86 degrees F (15 - 30 degrees C), 40k% RH].

Product Details

UPC / SKU 8 10047 39008 4

DSLD Entry Date 2023-05-24

Product Type Other Combinations

Form Capsule

Brand Nugenix

DSLD ID 285607

Data Updated 2026-04-11

Research Evidence

12 Research Sources

45 Avg Quality Score

6 Rct

5 Clinical Trial

1 Meta Analysis

C Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systematic review and meta-analysis of randomised controlled trials

Meta Analysis Journal of the International Society of Sports Nutrition 2021

PubMed DOI

C Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.

Rct Nutrients

PubMed DOI

C Effects of Acute Citrulline Malate Supplementation on CrossFit® Exercise Performance: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study.

Rct Nutrients

PubMed DOI

C Impact of L-Citrulline Supplementation and HIIT on Lipid Profile, Arterial Stiffness, and Fat Mass in Obese Adolescents with Metabolic-Dysfunction-Associated Fatty Liver Disease: A Randomized Clinical Trial.

Rct Nutrients

PubMed DOI

C Effect of L-Citrulline Supplementation on NAFLD in Adolescents With Obesity

Clinical Trial ClinicalTrials.gov 2021

ClinicalTrials.gov

C Effects of L-Citrulline or Citrulline-malate on Neuromuscular Performance in Resistance-trained Adults

Clinical Trial ClinicalTrials.gov 2022

ClinicalTrials.gov

C Acute effects of Nitrosigine® and citrulline malate on vasodilation in young adults.

Rct Journal of the International Society of Sports Nutrition

PubMed DOI

C Effects of Combined Versus Single Supplementation of Creatine, Beta-Alanine, and L-Citrulline During Short Sprint Interval Training on Basketball Players' Performance: A Double-Blind Randomized Placebo-Controlled Trial.

Rct International journal of sports physiology and performance

PubMed DOI

C Acute effects of combined supplementation of L-arginine and citrulline malate on aerobic, anaerobic, and CrossFit exercise performance.

Rct Scientific reports

PubMed DOI

C L-Citrulline in Peripheral Artery Disease

Clinical Trial ClinicalTrials.gov 2016

ClinicalTrials.gov

View all evidence for Citrulline →