NMN 500 mg by Vitamatic — Ingredients, Evidence & Safety

Product Label

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Safety Alerts

⚠️ Beta-Nicotinamide Mononucleotide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

The safety score is low because the 500mg dose of NMN is over 14 times higher than the recommended maximum daily limit of 35mg.

Label Data

2 Capsule(s) Serving Size

30 Servings

Non-Nutrient/Non-Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Beta-Nicotinamide Mononucleotide

500 mg

⚠️ Exceeds Tolerable Upper Intake Level by 14.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 500mg UL 35mg

Other Ingredients

Hypromellose Silicon Dioxide Magnesium Stearate Microcrystalline Cellulose

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (90% of products) Nutrient (2% of products)

Target Groups

Adult (18 - 50 Years) Sugar Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take 2 vegetable capsules daily with 8-12 oz of water or as directed by your healthcare provider.

⚠️ Warnings & Precautions

Caution: Consult with your healthcare provider if you are pregnant, nursing, taking any medications, or planning any medical procedures.

Do not use if safety seal is broken or missing.

Keep out of reach of children.

Do not exceed the recommended dose. Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

🧪 Formulation Notes

Free of sugar, starch, yeast, soy, wheat, egg, artificial colors, flavors, and preservatives.

Nicotinamide Mononucleotide

Promotes healthy aging and NAD+ production Supports energy metabolism and healthy brain function

Non GMO

Additional Information

Store in a cool, dry place.

GMP Good Manufacturing Practice Certified Made in U.S.A.

Product Details

UPC / SKU 8 10078 47118 9

DSLD Entry Date 2023-03-22

Product Type Non-Nutrient/Non-Botanical

Form Capsule

Brand Vitamatic

DSLD ID 283059

Data Updated 2026-04-11

Research Evidence

8 Research Sources

54 Avg Quality Score

4 Rct

2 Meta Analysis

2 Clinical Trial

B Efficacy of oral nicotinamide mononucleotide supplementation on glucose and lipid metabolism for adults: a systematic review with meta-analysis on randomized controlled trials

Meta Analysis Critical reviews in food science and nutrition 2025

PubMed DOI

B Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study

Rct GeroScience 2024

PubMed DOI

C Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.

Rct Science (New York, N.Y.)

PubMed DOI

C The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.

Rct GeroScience

PubMed DOI

C Effects of Nicotinamide Mononucleotide on Glucose and Lipid Metabolism in Adults: A Systematic Review and Meta-analysis of Randomised Controlled Trials

Meta Analysis Current diabetes reports 2024

PubMed DOI

C Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial

Rct Scientific reports 2023

PubMed DOI

C Safety and Pharmacokinetics of Nicotinamide Mononucleotide (NMN) in Healthy Adults.

Clinical Trial ClinicalTrials.gov 2021

ClinicalTrials.gov

C Effect of 'Nicotinamide Mononucleotide' (NMN) on Cardiometabolic Function

Clinical Trial ClinicalTrials.gov 2017

ClinicalTrials.gov

View all evidence for Nmn →