Home/ Supplements/ Berberine/ Berberine 500 mg

Berberine 500 mg

product on market Capsule Herbal Secrets Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Berberine HCl is supported by moderate to strong evidence for its role in managing blood glucose levels and improving insulin sensitivity. Research indicates it may help lower lipid levels and support metabolic health. The current evidence base for these effects is well-documented in clinical studies.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Berberine 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
120
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)

Other Ingredients

Rice Flour Microcrystalline Cellulose Magnesium Stearate Gelatin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, adults take one (1) capsule daily, preferably with a meal or as directed by a health care professional.

Warnings & Precautions

Caution: If you are pregnant or nursing, taking any medication(s) or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Formulation Notes

Herbal Secrets Berberine helps support a healthy immune system. Berberine also plays a role in regulating healthy glucose metabolism, which may support weight loss, detoxification, gastrointestinal function and improve heart health.

100% natural

Antioxidant properties Supports immune function Supports glucose metabolism Supports cardiovascular & gastrointestinal function

Contains no: shellfish, egg, fish, peanuts, milk, soy, tree nuts or wheat.

Herbal Secrets An FDA regulated facility

Additional Information

Visit us online @amazingnutrition.com

Made in the USA

GMP Good manufacturing practice Quality product

Store in a cool, dry place.

Vitamin angels Proud supporter

Metadata

Product Details

UPC / SKU8 19209 02247 4
DSLD Entry Date2023-03-22
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID282806
Data Updated2026-04-11
Research

Research Evidence

98
Research Sources
55
Avg Quality
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019 PubMed DOI
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023 PubMed DOI
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024 PubMed DOI
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025 PubMed DOI
View all evidence for Berberine →
Compare

Similar Products

View all Berberine products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.