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Tranquil Sleep

product on market Tablet or Pill Natural Factors Stress-Relax Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 60% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains L-theanine, 5-HTP, and melatonin, which are supported by moderate to strong evidence for promoting relaxation and sleep onset. These ingredients work by modulating neurotransmitters to support sleep quality and reduce stress. The overall evidence coverage for this specific profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Tranquil Sleep
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
60
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
15 Calorie(s)
Total Carbohydrates
3 Gram(s) (1% DV)
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
30 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Cane Sugar Stearic Acid Xylitol Silica Natural source flavors Citric Acid Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: Chew 2 tablets at bedtime or as directed by a health professional.

Warnings & Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication or supplements with serotonergic activity (specifically those with SSRIs, MOAs, or depressant/sedative affect), have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

Formulation Notes

Tranquil Sleep formula is a unique combination of compounds that support relaxation and enhance natural sleep quality. In a tasty, tropical fruit-flavored chewable tablet.

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Contains no artificial colors, preservatives, or sweeteners; no dairy, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.

Suitable for vegetarians/vegans.

5-HTP, Suntheanine & Melatonin

Advanced fast acting formula

Additional Information

ISURA Non-GMO Mass Spec Documentation Lab tested

For freshness, store in a cool, dry place.

Recyclable container and label.

Metadata

Product Details

UPC / SKU0 68958 02843 9
DSLD Entry Date2023-01-23
Product TypeOther Combinations
FormTablet or Pill
BrandNatural Factors Stress-Relax
DSLD ID282636
Data Updated2026-04-11
Research

Research Evidence

37
Research Sources
53
Avg Quality
22
Rct
10
Systematic Review
3
Meta Analysis
1
Clinical Trial
1
Openfda Safety
B Examining the effect of L-theanine on sleep: a systematic review of dietary supplementation trials
Systematic Review Nutritional neuroscience 2026 PubMed DOI
B The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis
Meta Analysis Sleep medicine reviews 2025 PubMed DOI
B The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness
Rct Nutritional neuroscience 2010 PubMed DOI
B Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial
Rct Nutrients 2019 PubMed DOI
B The Role of Supplements and Over-the-Counter Products to Improve Sleep in Children: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrition reviews 2025 PubMed DOI
B Effect of Alpha-S1-Casein Tryptic Hydrolysate and L-Theanine on Poor Sleep Quality: A Double Blind, Randomized Placebo-Controlled Crossover Trial
Rct Nutrients 2022 PubMed DOI
B Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study
Rct Nutritional neuroscience 2025 PubMed DOI
B The combined effects of L-theanine and caffeine on cognitive performance and mood
Rct Nutritional neuroscience 2008 PubMed DOI
B Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2014 PubMed DOI
View all evidence for L Theanine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.