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Berberine HCL 400 mg

product on market Capsule Good State Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Berberine hydrochloride has moderate to strong evidence for supporting glycemic control and improving insulin sensitivity. Research indicates it may help lower blood glucose levels by activating AMP-activated protein kinase. The ingredient is generally recognized as safe for short-term use in healthy adults.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Berberine HCL 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
120
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 500.0mg (234 products) 95 studies (A:0, B:35)

Other Ingredients

Rice Flour Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Try taking with liquid ionic blood sugar support (SKU #208) for additional support. For increased blood sugar control, try glycox 500.

Directions: Adults: Take one capsule 15 minutes before meals containing carbohydrates.

Do not exceed 3 capsules daily. Works well with breakfast, pre-workout, and/or post-workout meals.

It can take 2 to 3 capsules a day for 2 weeks to see results. Results will vary.

Shake well before using.

Warnings & Precautions

Children: under 4, please consult a physician.

Caution: Keep out of reach of children.

Always speak with your physician before using any dietary supplement. Do not use if tamper-evident seal is broken or missing.

Formulation Notes

Berberine was made to help remove glucose/sugar from the blood stream and move it into the muscle while avoiding fat. This product is made with high quality berberine HCL and not berberine sulfate.

This product is made with high quality berberine HCL and not berberine sulfate.

Formulated for cholesterol & blood sugar balance

Contains 400 mg berberine HCL

Good state is proud to follow Good Manufacturing Practices (GMP)

Additional Information

If you have been thinking about your weight, blood sugar and cholesterol a lot lately, and you are looking for more support and balance in your life, think about berberine!

Made in USA

100% satisfaction guaranteed

Professional grade

For freshness, keep refrigerated after opening, or store in a cool, dark place.

Note: No product claims are being made or implied. Research is ongoing.

Text Support +1-215-608-1124 X0016OOV5Z FBA USA

Metadata

Product Details

UPC / SKU8 56442 00612 0
DSLD Entry Date2022-10-24
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID276979
Data Updated2026-04-11
Research

Research Evidence

98
Research Sources
55
Avg Quality
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019 PubMed DOI
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023 PubMed DOI
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024 PubMed DOI
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025 PubMed DOI
View all evidence for Berberine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.