🟡 60/100

Review before taking

  • Nicotinamide: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Safety Alerts

⚠️ Nicotinamide: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)

This product has a low safety score because the dose of nicotinamide is significantly higher than the recommended maximum daily limit.

Label Data

1 Sustained Release Tablet(s) Serving Size
60 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

1000 mg (6250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 28.6× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 1000mg UL 35mg

Other Ingredients

Stearic Acid Dicalcium Phosphate Rice Bran Hydroxypropyl Methylcellulose Magnesium Stearate Silica Pharmaceutical Glaze

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested usage: As a dietary supplement take one tablet daily.

⚠️ Warnings & Precautions

Caution: For adults only.

Consult a physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do not eat freshness packet. Keep in bottle.

🧪 Formulation Notes

Nicotinamide is a water-soluble amide of nicotinic acid. It is an essential member of the B-vitamin family and it does not cause a niacin flush. Biophix Maximum Strength Nicotinamide has been formulated to produce a gradual release over a prolonged period of time using a proprietary Micro-Sphere Sustained Release System. Nicotinamide and niacin are two different forms of vitamin B-3.

Made in USA Manufactured In A GMP Inspected Facility

Maximum Strength Nicotinamide 1,000 mg

Micro-Sphere Sustained Release System Flush-free sustained release GMP tested

High potency vitamin, gluten free

High potency vitamin, gluten free

Vegan

Free from artificial colors, flavoring, sweeteners, and preservatives. Free from the common allergens wheat, corn, soy and milk. Not manufactured with gluten, titanium dioxide, carnauba wax, talc, yeast, hexane. Hypo-allergenic.

Free from artificial colors, flavoring, sweeteners, and preservatives. Free from the common allergens wheat, corn, soy and milk. Not manufactured with gluten, titanium dioxide, carnauba wax, talc, yeast, hexane. Hypo-allergenic.

Gluten free GMO free

GMP tested

Additional Information

Made in USA Manufactured In A GMP Inspected Facility

Product Details

UPC / SKU X00161CUPL
DSLD Entry Date 2022-09-22
Product Type Vitamin
Form Tablet or Pill
Brand Biophix
DSLD ID 276051
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

Compare Similar Products

View all Niacin products →