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Nicotinamide 1000 mg

product on market Tablet or Pill Biophix Safety: 60/100
60/100

Review before taking

  • Nicotinamide: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Nicotinamide is a form of vitamin B3 that supports cellular energy metabolism and DNA repair, with strong evidence for its role in systemic health. However, a safety score of 60 suggests potential concerns regarding high-dose supplementation. Users should be aware of possible adverse effects associated with this 1000 mg concentration.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Nicotinamide: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 1000mg of Nicotinamide, which is nearly 29 times higher than the recommended upper intake limit of 35mg.

Label

Product Label

Label for Nicotinamide 1000 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Sustained Release Tablet(s)
Serving Size
60
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1000 mg (6250% DV)
Exceeds UL by 28.6× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Stearic Acid Dicalcium Phosphate Rice Bran Hydroxypropyl Methylcellulose Magnesium Stearate Silica Pharmaceutical Glaze
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: As a dietary supplement take one tablet daily.

Warnings & Precautions

Caution: For adults only.

Consult a physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do not eat freshness packet. Keep in bottle.

Formulation Notes

Nicotinamide is a water-soluble amide of nicotinic acid. It is an essential member of the B-vitamin family and it does not cause a niacin flush. Biophix Maximum Strength Nicotinamide has been formulated to produce a gradual release over a prolonged period of time using a proprietary Micro-Sphere Sustained Release System. Nicotinamide and niacin are two different forms of vitamin B-3.

Made in USA Manufactured In A GMP Inspected Facility

Maximum Strength Nicotinamide 1,000 mg

Micro-Sphere Sustained Release System Flush-free sustained release GMP tested

High potency vitamin, gluten free

High potency vitamin, gluten free

Vegan

Free from artificial colors, flavoring, sweeteners, and preservatives. Free from the common allergens wheat, corn, soy and milk. Not manufactured with gluten, titanium dioxide, carnauba wax, talc, yeast, hexane. Hypo-allergenic.

Free from artificial colors, flavoring, sweeteners, and preservatives. Free from the common allergens wheat, corn, soy and milk. Not manufactured with gluten, titanium dioxide, carnauba wax, talc, yeast, hexane. Hypo-allergenic.

Gluten free GMO free

GMP tested

Additional Information

Made in USA Manufactured In A GMP Inspected Facility

Metadata

Product Details

UPC / SKUX00161CUPL
DSLD Entry Date2022-09-22
Product TypeVitamin
FormTablet or Pill
BrandBiophix
DSLD ID276051
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.