Double Strength Glucosamine Chondroitin by Nature's Blend — Ingredients, Evidence & Safety

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

3 Softgel(s) Serving Size

20 Servings

Other Combinations Product Type

14% Evidence Coverage

Supplement Facts — Evidence Check

Calories

25 Calorie(s)

Total Fat

1.5 Gram(s) (2% DV)

Protein

1 Gram(s) (1% DV)

Manganese

2 mg (87% DV)

✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 2mg UL 11mg

Sodium

45 mg (2% DV)

Glucosamine HCl

1400 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 1400mg

Proprietary Blend

1315 mg

Other Ingredients

Soybean Oil Gelatin Glycerin Soy Lecithin Water, Purified

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take three softgels daily, preferably with a meal or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Keep out of the reach of children.

Double safety sealed for your protection. Do not use if either seal is broken or missing.

Caution: Contains fish (menhaden), shell fish (shrimp and crab), and soy ingredients. If you are allergic to any of these ingredients, please consult your healthcare professional before taking this product.

🧪 Formulation Notes

Preservative & gluten free. No sugar, salt, artificial colors, artificial flavors, wheat, yeast, or corn added.

This product is manufactured under strict quality control guidelines; therefore, purity and label potency are guaranteed. Made in USA & American Owned

Additional Information

Store in a cool, dry place.

Similar to Osteo Bi-Flex

Product Details

UPC / SKU 0 79854 09027 7

DSLD Entry Date 2022-11-22

Product Type Other Combinations

Form Softgel Capsule

Brand Nature's Blend

DSLD ID 274640

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →