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5-HTP 50 mg

product on market Capsule Metabolic Maintenance Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

5-HTP and Vitamin B6 are used to support serotonin synthesis, while glycine acts as a cofactor in this process. Research provides moderate evidence for the role of these ingredients in mood regulation. The overall evidence coverage for this specific profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 50 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

3 mg (176% DV)
2.3× RDA — within safe limits 114 studies (A:3, B:35)
50 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
Glycine
220 mg

Other Ingredients

Vegetarian Cellulose Capsule
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Directions: One (1) capsule daily, or as directed by a healthcare professional. Best taken between meals or at bedtime.

Warnings & Precautions

Caution: Do not take with MAO inhibitors or tricyclic antidepressants.

Pregnant or lactating women, consult your healthcare professional before taking this product.

Keep tightly closed in a cool, dry place, out of the reach of children.

Formulation Notes

Egg free Gluten free Free of nuts Dairy free

Manufactured in a GMP Compliant Facility

Additional Information

Keep tightly closed in a cool, dry place, out of the reach of children.

Metadata

Product Details

UPC / SKU8 38287 00100 3
DSLD Entry Date2022-09-22
Product TypeOther Combinations
FormCapsule
BrandMetabolic Maintenance
DSLD ID273943
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.