🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Capsule(s) Serving Size
90 Servings
Amino acid/Protein Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

100 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 100mg

Other Ingredients

Microcrystalline Cellulose Modified Cellulose Rice Extract Rice concentrate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Use: Take 1 capsule daily, at bedtime, preferably on an empty stomach. Best when taken as directed by a qualified healthcare professional.

⚠️ Warnings & Precautions

Warnings: Keep out of reach of children.

Consult with a physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements. 5-HTP should not be used by individuals taking anti-depressant medications such as MAO Inhibitors (MAOIs) or Selective Serotonin Re-uptake Inhibitors (SSRIs). May cause drowsiness and mild digestive upset.

Sealed for your protection> Do no use if seal is missing or broken.

Produced in a third-party, audited and registered cGMP compliant facility that may process other products that contain these allergens or ingredients.

🧪 Formulation Notes

Sourced from Switzerland Supports Healthy Mood

Formulated to contain No Gluten No GMOs No Soy

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten.

Additional Information

Best stored at controlled room temperature 20 degrees C to 25 degrees C (68 degrees F to 77 degrees F).

All California Gold Nutrition products come with a 100% Gold Guarantee. If you are not completely satisfied with your purchase, return the unused portion within 90 days for a full refund.

Product Details

UPC / SKU 8 98220 01173 5
DSLD Entry Date 2022-06-16
Product Type Amino acid/Protein
Form Capsule
DSLD ID 272855
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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