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5-HTP 100 mg

product on market Capsule California Gold Nutrition Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-HTP serves as a precursor to serotonin and is used in research to support mood regulation and sleep. There is moderate evidence suggesting its efficacy for managing certain depressive symptoms. However, overall evidence coverage for this specific formulation remains limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
90
Servings
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Microcrystalline Cellulose Modified Cellulose Rice Extract Rice concentrate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take 1 capsule daily, at bedtime, preferably on an empty stomach. Best when taken as directed by a qualified healthcare professional.

Warnings & Precautions

Warnings: Keep out of reach of children.

Consult with a physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements. 5-HTP should not be used by individuals taking anti-depressant medications such as MAO Inhibitors (MAOIs) or Selective Serotonin Re-uptake Inhibitors (SSRIs). May cause drowsiness and mild digestive upset.

Sealed for your protection> Do no use if seal is missing or broken.

Produced in a third-party, audited and registered cGMP compliant facility that may process other products that contain these allergens or ingredients.

Formulation Notes

Sourced from Switzerland Supports Healthy Mood

Formulated to contain No Gluten No GMOs No Soy

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten.

Additional Information

Best stored at controlled room temperature 20 degrees C to 25 degrees C (68 degrees F to 77 degrees F).

All California Gold Nutrition products come with a 100% Gold Guarantee. If you are not completely satisfied with your purchase, return the unused portion within 90 days for a full refund.

Metadata

Product Details

UPC / SKU8 98220 01173 5
DSLD Entry Date2022-06-16
Product TypeAmino acid/Protein
FormCapsule
DSLD ID272855
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.