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Calcium + D3

product on market Other (e.g. tea bag) Os-Cal Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Calcium and vitamin D3 are supported by strong evidence for maintaining bone density and supporting skeletal health. Vitamin D3 facilitates the intestinal absorption of calcium to optimize bone mineralization. However, the overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Calcium + D3
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Caplet(s)
Serving Size
105
Servings
Single Vitamin and Mineral
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

200 IU (50% DV)
Within RDA (0.3× RDA) 608 studies (A:16, B:251)
Calcium
500 mg (50% DV)

Other Ingredients

Calcium Carbonate Corn Syrup solids Talc Corn Starch Sodium Starch Glyconate Polysorbate 80 Polyvinyl Alcohol Polyethylene Glycol 3350 Titanium Dioxide Yellow 5 Lake Blue 1 Lake Calcium Stearate Methylparaben Propylparaben Gelatin Sucrose Vitamin D3 DL-Alpha Tocopherol
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Approved Health
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one caplet, twice a day, with meals, or as recommended by your physician. Elderly patients or those with difficulty with swallowing are recommended to take the caplet with a large glass of water (8 oz) to minimize the risk of choking. Caplets may be broken in half. Can be taken along with your multivitamin.

Warnings & Precautions

Elderly patients or those with difficulty with swallowing are recommended to take the caplet with a large glass of water (8 oz) to minimize the risk of choking.

Keep out of the reach of children.

Important: Do not use if foil inner seal printed "sealed for your protection" is disturbed or missing.

Formulation Notes

Be strong with Os-Cal

500 mg calcium 200 IU vitamin D3

May help reduce the risk of osteoporosis

Adds a dietarily insignificant amount of sugar. Adds a dietarily insignificant amount of sodium. Each caplet provides 500 mg of elemental calcium.

Reasons to choose Os-Cal: Effective in helping maintain strong healthy bones Meets USP dissolution standards

Highly absorbable calcium

This Os-Cal Calcium+D3 has no sugar, lactose, carbohydrates or sodium

Osteoporosis Adequate calcium and vitamin D as part of a healthful diet, along with physical activity, may reduce the risk of osteoporosis in later life.

Additional Information

Value size GSK

Store below 25 degrees C (77 degrees F). Keep container tightly closed.

Questions or comments? call toll-free 1-800-2451040 (English/Spanish) weekdays

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Metadata

Product Details

UPC / SKU3 0766-1656-75 2
DSLD Entry Date2022-09-22
Product TypeSingle Vitamin and Mineral
FormOther (e.g. tea bag)
BrandOs-Cal
DSLD ID272482
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.