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D3 125 mcg 5000 IU

product on market Softgel Capsule Nature Made Safety: 60/100
60/100

Review before taking

  • Vitamin D3: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin D3 is supported by strong evidence for maintaining calcium homeostasis and bone health. However, the low safety score suggests potential concerns regarding high-dose supplementation. Users should be mindful of toxicity risks associated with excessive intake.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin D3: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a lower score because the amount of Vitamin D3 exceeds the recommended daily upper limit for safety.

Label

Product Label

Label for D3 125 mcg 5000 IU
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
90
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

125 mcg (625% DV)
Exceeds UL by 1.2× (UL: 0.1 mg) 608 studies (A:16, B:251)

Other Ingredients

Soybean Oil Gelatin Glycerin Water Corn Oil
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Take one softgel daily with a meal. For easier swallowing, take with water before and during ingestion.

Warnings & Precautions

Suggested Use: This is a high dose vitamin D product for those with higher vitamin D needs and/or deficiency, as determined by a healthcare professional. Consult with your healthcare professional before use.

Store tightly closed, in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: Use only as directed by your healthcare professional. Do not exceed one softgel daily or take with other supplements containing vitamin D, such as multivitamins with vitamin D. Do not take if you are pregnant, nursing or have kidney disease, hypercalcemia (high blood calcium) or may have sensitivity to hypercalcemia (such as cancer, hyperparathyroidism, sarcoidosis or other granulomatous disorders), unless recommended by a health care professional.

Formulation Notes

Extra strength Equivalent to 5000 IU Supports bone, teeth, muscle and immune health

No color added No artificial flavors Gluten free

USP has tested and verified ingredients, potency, and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org Based on Pharmacy Times Survey of pharmacists recommending Letter Vitamin Supplements.

Additional Information

#1 pharmacist recommended

USP Dietary Supplement Verified

Store tightly closed, in a cool, dry place, out of reach of children.

Metadata

Product Details

UPC / SKU0 31604 02621 9
DSLD Entry Date2022-08-23
Product TypeVitamin
FormSoftgel Capsule
DSLD ID271464
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.