E-400 by AvPAK — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Softgel(s) Serving Size

30 Servings

Vitamin Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin E

400 IU (1333% DV)

📊 17.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 268.0mg UL 1000mg

Other Ingredients

Gelatin Glycerin Soybean Oil purified Water

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (98% of products) Structure/Function (81% of products) Nutrient (56% of products) Qualified Health (2% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: As a vitamin supplement, take one (1) or two (2) softgels daily with any meal for maximum results, or as directed by your healthcare provider. Do not exceed recommended dosage.

⚠️ Warnings & Precautions

Contains a soy ingredient.

Warning: Before using this product, consult your healthcare provider. If you are: pregnant or nursing, have a medical condition, taking any medications, or are planning any medical procedures.

If any adverse reactions occur, discontinue use and consult your healthcare provider.

Keep out of reach of children.

Do not use if product appears to be tampered with or the seal is broken.

🧪 Formulation Notes

Immune and Heart Support

No added sugar, salt, yeast, preservatives, artificial flavors, or colors.

Vitamin E is an essential nutrient to support immune and heart function.

AvKare's manufacturer offers the highest quality ingredients produced to strict standards of quality for support of your good health.

Additional Information

50268-870-13 30 Softgels (3 x 10) Unit Dose

Store in a cool dry place.

See us at www.avkare.com for more information.

Product Details

UPC / SKU 5026887013

DSLD Entry Date 2022-07-21

Product Type Vitamin

Form Softgel Capsule

Brand AvPAK

DSLD ID 271325

Data Updated 2026-04-11

Research Evidence

253 Research Sources

55 Avg Quality Score

128 Meta Analysis

52 Systematic Review

41 Rct

24 Clinical Trial

3 Regulatory Source

1 Narrative Review

1 Other

1 Guideline

1 Openfda Safety

A Vitamin E supplementation in pregnancy

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Systematic Review The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin E for Alzheimer's disease and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2008

PubMed DOI Cochrane

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

A Exercise for intermittent claudication

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis

Meta Analysis Nutritional neuroscience 2021

PubMed DOI

A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis

Meta Analysis European journal of clinical nutrition 2023

PubMed DOI

A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

Rct JAMA 2011

PubMed DOI

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.

Guideline JAMA 2022

PubMed DOI

View all evidence for Vitamin E →