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Melatonin + 200 mg L-Theanine

product on market Softgel Capsule Nature Made Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Melatonin and L-theanine are supported by moderate to strong evidence for promoting sleep and relaxation. Melatonin helps regulate sleep-wake cycles, while L-theanine is associated with reduced anxiety and improved sleep quality. These ingredients are generally well-tolerated and maintain a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Melatonin + 200 mg L-Theanine
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
60
Servings
Non-Nutrient/Non-Botanical
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
200 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Medium Chain Triglyceride Gelatin Glycerin Rapeseed Lecithin Beeswax Water Colors added
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take one Melatonin + L-theanine softgel one hour before bedtime. Do not exceed one softgel daily unless recommended by a healthcare professional. For easier swallowing, take with water before and during ingestion.

Warnings & Precautions

Keep out of the reach of children.

Do not use if imprinted seal under cap is broken or missing.

Warning: This product contains melatonin.

Do not use this product unless advised by a physician if you are pregnant, attempting to become pregnant, or nursing; or if you are taking any medications or have any chronic disease, including hypertension (high blood pressure), diabetes, or an endocrine, auto-immune, depressive, bleeding or seizure disorder.

Side effects may include headaches, dizziness, nausea or loss of appetite. Do not take melatonin while operating a motor vehicle or machinery.

Not intended for individuals under the age of 18.

Consult a health care professional if you are experiencing persistent sleep difficulties. Do not drive or operate machinery within eight hours of taking this product or if you feel groggy. Consult a healthcare professional for use beyond four weeks.

Formulation Notes

3 mg Melatonin

Natural Acting Sleep Aid Ingredients to help relax the mind and support sleep Fall Asleep Naturally

100% drug free

Nature Made Melatonin + 200 mg L-theanine contains 3 mg of melatonin, which naturally occurs in your body. Helps regulate sleep cycles L-theanine is clinically shown to help relax the mind

Nature Made Melatonin + L-theanine contains two ingredients to help support sleep - L-theanine and melatonin. L-theanine is an amino acid, which was originally discovered as a constituent of green tea in 1949, and is now used in its synthetic and natural form globally. Clinical studies show L-theanine helps relax the mind. Melatonin plays a natural role in the body's sleep cycle. Both ingredients can help you fall asleep naturally.

Colors derived from natural sources - no synthetic dyes No artificial flavors No yeast or starch Gluten free

Melatonin + L-theanine softgels are made to Nature Made’s guaranteed purity and potency standards. Provides ingredients that work with your body to help you fall asleep without drugs.

Encapsulated and Quality Tested in the U.S.A.

A good night of sleep helps us to wake up feeling refreshed and ready to get on with our day. Melatonin is a hormone produced in the pineal gland that helps to regulate the body's natural biorhythm, or sleep/wake cycle. L-theanine is an amino acid naturally found in green tea, and now used in its synthetic and natural form globally. L-theanine is clinically shown to increase the alpha wave activity in the brain to help relax the mind.

Nature Made Melatonin + 200 mg L-Theanine helps to relax your mind and help you fall asleep, naturally. Nature Made Melatonin + 200 mg L-Theanine is guaranteed to meet our high quality standards - it is made from carefully selected ingredients under strict manufacturing processes.

No preservatives

Additional Information

Nature Made product formulas may change from time to time. Please consult the label on the product that you purchased for product composition information.

Store in a cool, dry place.

Metadata

Product Details

DSLD Entry Date2022-07-21
Product TypeNon-Nutrient/Non-Botanical
FormSoftgel Capsule
DSLD ID271095
Data Updated2026-04-11
Research

Research Evidence

37
Research Sources
53
Avg Quality
22
Rct
10
Systematic Review
3
Meta Analysis
1
Clinical Trial
1
Openfda Safety
B Examining the effect of L-theanine on sleep: a systematic review of dietary supplementation trials
Systematic Review Nutritional neuroscience 2026 PubMed DOI
B The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis
Meta Analysis Sleep medicine reviews 2025 PubMed DOI
B The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness
Rct Nutritional neuroscience 2010 PubMed DOI
B Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial
Rct Nutrients 2019 PubMed DOI
B The Role of Supplements and Over-the-Counter Products to Improve Sleep in Children: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrition reviews 2025 PubMed DOI
B Effect of Alpha-S1-Casein Tryptic Hydrolysate and L-Theanine on Poor Sleep Quality: A Double Blind, Randomized Placebo-Controlled Crossover Trial
Rct Nutrients 2022 PubMed DOI
B Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study
Rct Nutritional neuroscience 2025 PubMed DOI
B The combined effects of L-theanine and caffeine on cognitive performance and mood
Rct Nutritional neuroscience 2008 PubMed DOI
B Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2014 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.