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NMN 12000 400 mg

product on market Capsule Doctor's Best Safety: 60/100
60/100

Review before taking

  • Beta-Nicotinamide Mononucleotide: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Beta-Nicotinamide Mononucleotide is researched for its role in boosting NAD+ levels to support cellular energy. Evidence for these effects in humans remains limited. Due to a lower safety score, potential concerns regarding long-term tolerability should be noted.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Beta-Nicotinamide Mononucleotide: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 400mg of Beta-Nicotinamide Mononucleotide, which is over 11 times the recommended upper limit of 35mg.

Label

Product Label

Label for NMN 12000 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Veggie Capsule(s)
Serving Size
30
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Exceeds UL by 11.4× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Rice Flour Hypromellose Magnesium Stearate Silicon Dioxide Pectin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Adult Use: Take 2 capsules daily.

Warnings & Precautions

Warning: Not recommended for children.

Consult a physician before use if you are pregnant, nursing, have a medical condition or taking any medications.

Keep out of reach of children.

Formulation Notes

Nicotinamide Mononucleotide (NMN) is the precursor to Nicotinamide Adenine Dinucleotide (NAD+), an essential component of the cellular processes to support various metabolic functions. As we age, NAD+ levels decline in the body, decreasing the mitochondrial sirtuins which may play a role in healthy aging.

400 mg per serving

Supports healthy aging, energy, and NAD+ production

Supports Healthy aging and NAD+ production Stimulates energy production Metabolic functions

Additional Information

Store in a cool fry place.

Made in the USA

Metadata

Product Details

UPC / SKU7 53950 00577 8
DSLD Entry Date2022-06-16
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID270688
Data Updated2026-04-11
Research

Research Evidence

8
Research Sources
54
Avg Quality
4
Rct
2
Meta Analysis
2
Clinical Trial
B Efficacy of oral nicotinamide mononucleotide supplementation on glucose and lipid metabolism for adults: a systematic review with meta-analysis on randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2025 PubMed DOI
B Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study
Rct GeroScience 2024 PubMed DOI
C Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.
Rct Science (New York, N.Y.) PubMed DOI
C The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.
Rct GeroScience PubMed DOI
C Effects of Nicotinamide Mononucleotide on Glucose and Lipid Metabolism in Adults: A Systematic Review and Meta-analysis of Randomised Controlled Trials
Meta Analysis Current diabetes reports 2024 PubMed DOI
C Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial
Rct Scientific reports 2023 PubMed DOI
C Safety and Pharmacokinetics of Nicotinamide Mononucleotide (NMN) in Healthy Adults.
Clinical Trial ClinicalTrials.gov 2021
C Effect of 'Nicotinamide Mononucleotide' (NMN) on Cardiometabolic Function
Clinical Trial ClinicalTrials.gov 2017
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.