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Magnesium Oxide 500 mg

product on market Tablet or Pill Best Naturals Safety: 60/100
60/100

Review before taking

  • Magnesium: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Magnesium is supported by strong evidence for its role in nerve function and muscle support. However, the low safety score suggests potential concerns regarding gastrointestinal tolerance or drug interactions. This formulation provides a concentrated dose of magnesium oxide for supplementation.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of magnesium exceeds the recommended daily upper limit for adults.

Label

Product Label

Label for Magnesium Oxide 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
180
Servings
Mineral
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (119% DV)
Exceeds UL by 1.4× (UL: 350 mg) 316 studies (A:8, B:159)

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Croscarmellose Sodium Stearic Acid Magnesium Stearate Silicon Dioxide Pharmaceutical Glaze
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, take one (1) tablet two times daily with food or as directed by your qualified healthcare professional. Consider taking these other Best Naturals products: Calcium, Vitamin D and Zinc.

Warnings & Precautions

Caution: For adults only, if you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Formulation Notes

Magnesium oxide is derived from ancient oceanic deposits and is a rich source of element magnesium (58% average). Magnesium is an essential mineral that plays a key role in the activation of amino acid for protein biosynthesis and is highly concentrated in intracellular fluid and bone. Certain research publications indicate that Magnesium Oxide may help support the following: Supports energy production and metabolism. Supports essential nerve, muscle and heart function. Supports healthy blood circulation.

Premium formula

3rd party lab tested

No artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no corn, no soy, no egg, no lactose, no gluten, no wheat, no yeast, no fish.

Additional Information

Keep in cool, dry place.

Made in USA

GMP Good Manufacturing Practice Product

Metadata

Product Details

UPC / SKU8 17716 01348 0
DSLD Entry Date2022-06-16
Product TypeMineral
FormTablet or Pill
DSLD ID269874
Data Updated2026-04-11
Research

Research Evidence

7
Research Sources
45
Avg Quality
6
Rct
1
Meta Analysis
C Effectiveness and safety of polyethylene-glycol-4000 versus sodium picosulphate plus magnesium oxide and citric acid for bowel cleansing before colonoscopy in children: A systematic review with meta-analysis
Meta Analysis Journal of pediatric gastroenterology and nutrition 2025 PubMed DOI
C A randomized controlled study of effects of dietary magnesium oxide supplementation on bone mineral content in healthy girls
Rct The Journal of clinical endocrinology and metabolism 2006 PubMed
C Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial
Rct The American journal of gastroenterology 2021 PubMed DOI
C The efficacy of magnesium oxide and sodium valproate in prevention of migraine headache: a randomized, controlled, double-blind, crossover study.
Rct Acta neurologica Belgica PubMed DOI
C A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
Rct Nutrition journal PubMed DOI
C Comparative study between manitol and sodium picosulfate with magnesium oxide solutions in the preparation for colonoscopy.
Rct Revista do Colegio Brasileiro de Cirurgioes PubMed DOI
C Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.
Rct Magnesium research PubMed DOI
View all evidence for Magnesium Oxide →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.