Double-Strength SAM-e 400 mg
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 100% of ingredients have research evidence
Product Label
Have a supplement label? Find it here.
Upload a photo of any supplement label to search our database of 92,312 products.
Label Data
Supplement Facts — Evidence Check
Other Ingredients
Label Claims — Verification
Target Groups
Product Information
📋 Directions for Use
Suggested Adult Use: Take 1 tablet daily between meals, or as recommended by a nutritionally informed physician. Do not chew or crush tablet.
⚠️ Warnings & Precautions
Warning: Individuals using antidepressant medications should consult with their prescribing physician prior to using this product.
Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe.
Do not use if pregnant or nursing.
May cause gastrointestinal discomfort in a small percentage of people.
🧪 Formulation Notes
Helps support mood and neural function Helps support joint comfort and mobility Helps support liver health and detoxification
Vegetarian
Non-GMO Gluten free Soy free
Doctor’s Best SAM-e helps replenish your SAM-e levels and promote a healthy mood. SAM-e (S-Adenosyl-L-Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody. Supplementing with SAM-e Soloesse Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate biochemical activity in the human body.
SAM-e and Mood and Cognitive Function SAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body’s antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.
SAM-e and Joint Function In clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.
SAM-e and Liver Function SAM-e helps support healthy levels of glutathione, a critical antioxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.
Doctor's Best utilizes only the highest quality Italian Soloesse SAM-e providing slow and targeted release for improved GI tolerance and absorption. Our Double-Strength SAM-e 400 contains 400 mg of active Soloesse SAM-e in each tablet. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.
Additional Information
Store in a cool dry place.
Double Strength SAM-e is sealed in blister packs for freshness and stability.
Product Details
Research Evidence
We're building the evidence profile for this product's ingredients.
Our team is working to connect every product on the American market with peer-reviewed research. Check back soon for evidence-backed analysis.