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5-HTP 50 mg

product on market Capsule Healthy Origins Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-HTP serves as a precursor to serotonin and is supported by moderate evidence for its role in managing depressive symptoms. Research suggests it may help regulate mood and sleep patterns. The ingredient profile maintains a high safety rating for typical use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 50 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Veggie Capsule(s)
Serving Size
60
Servings
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Rice Flour Vegetable Capsule
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults: Take one (1) veggie capsules once or twice daily, preferably on an empty stomach, or as directed by a physician.

Warnings & Precautions

Caution: Do not use if you are pregnant, nursing, or have a medical condition. If you are taking anti-depressant SSRI's, MAOI's, or sedatives, please contact a physician before use.

May cause drowsiness.

Formulation Notes

Healthy Origins 5-HTP (5-Hydroxytryptophan) is a naturally occurring substance extracted from the seeds of the Griffonia simplicifolia plant. 5-HTP is a precursor to serotonin which is a vital neurotransmitter in the body.

Serotonin is one of the primary neurotransmitters which supports healthy mood, appetite, and sleep.

Healthy Origins 5-HTP is guaranteed to be free of the "peak x" contaminant.

Non-GMO Soy-free

Naturally sourced Supports a positive mood

Vegetarian formula

Does not contain sugar, yeast, wheat, gluten, soy, barley, fish, shellfish, peanuts, egg or milk. No artificial sweeteners, flavors, colors or preservatives.

Metadata

Product Details

UPC / SKU6 03573 35071 0
DSLD Entry Date2022-06-16
Product TypeAmino acid/Protein
FormCapsule
DSLD ID268845
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.