Home/ Supplements/ Vitamin B12/ Methylcobalamin (Vitamin B-12)

Methylcobalamin (Vitamin B-12)

product on market Tablet or Pill DC Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Methylcobalamin is a bioactive form of vitamin B12 that supports neurological function and red blood cell formation. There is strong evidence supporting its role in maintaining nerve health and preventing megaloblastic anemia. This ingredient is generally well-tolerated with a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Methylcobalamin (Vitamin B-12)
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
30
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5000 mcg (208333% DV)
2083.3× RDA — above typical dose 139 studies (A:1, B:44)

Other Ingredients

Mannitol natural Cherry flavors Stearic Acid Vegetable Cellulose Vegetable Magnesium Stearate Silica Stevia Citric Acid
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take 1 tablet daily. Allow tablet to dissolve under tongue.

Warnings & Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing do not take this product.

Formulation Notes

Methylcobalamin is the form of vitamin B-12 active in the central and peripheral nervous system. The liver may not convert the common form of vitamin B-12 (cyanocobalamin) into adequate amounts of methylcobalamin needed for proper neuronal functioning.

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Vegetarian/vegan

Gluten free

Nutritionally supports healthy blood cells & nervous system

Made in USA

Additional Information

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

Quali Pure

Metadata

Product Details

DSLD Entry Date2022-04-11
Product TypeVitamin
FormTablet or Pill
BrandDC
DSLD ID267231
Data Updated2026-04-11
Research

Research Evidence

237
Research Sources
53
Avg Quality
83
Meta Analysis
74
Systematic Review
45
Rct
29
Clinical Trial
2
Guideline
2
Regulatory Source
1
Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021 PubMed DOI
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024 PubMed DOI
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020 PubMed DOI
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024 PubMed DOI
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024 PubMed DOI
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023 PubMed DOI
View all evidence for Vitamin B12 →
Compare

Similar Products

B-12 100 mcg
Vitamin World · Tablet or Pill
100
B-12 500 mcg
Vitamin World · Tablet or Pill
100
High Potency B12 250 mcg
Sundown Naturals · Tablet or Pill
100
High Potency 500 mcg Vitamin B-12
Equaline · Tablet or Pill
100
Vitamin B12 100 mcg
Sunmark · Tablet or Pill
100
View all Vitamin B12 products →
Vitamin B12 research Best Vitamin B12 All Vitamin B12 products More from DC View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.