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E 400 IU (180 mg)

product on market Softgel Capsule Nature Made Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin E acts as an antioxidant to protect cells from oxidative stress. Research provides moderate evidence for its role in supporting immune function and skin health. This specific formulation maintains a high safety profile for general use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for E 400 IU (180 mg)
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
300
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

180 mg (1200% DV)
12.0× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)

Other Ingredients

Gelatin Glycerin Water
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Adults, take 1 softgel daily with water and a meal.

Warnings & Precautions

Store tightly, in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: If you are pregnant, nursing, taking medication, have vascular disease or blood clotting issues, consult your physician before use.

Formulation Notes

Dl-Alpha Antioxidant & essential nutrient

No color added No artificial flavors No added preservatives Gluten free

USP has tested and verified ingredients, potency and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org

Dl-Alpha is the synthetic form of Vitamin E. For our plant based product, purchase Nature Made plant Sourced Vitamin E.

Additional Information

#1 pharmacist recommended vitamin & supplement brand Value size

USP Verified Dietary Supplement

Store tightly closed, in a cool, dry place, out of reach of children.

Based on Pharmacy Times survey of pharmacists recommending Letter Vitamin Supplements.

Metadata

Product Details

UPC / SKU0 31604 01882 5
DSLD Entry Date2022-02-23
Product TypeVitamin
FormSoftgel Capsule
BrandNature Made
DSLD ID266975
Data Updated2026-04-11
Research

Research Evidence

253
Research Sources
55
Avg Quality
128
Meta Analysis
52
Systematic Review
41
Rct
24
Clinical Trial
3
Regulatory Source
1
Narrative Review
1
Other
1
Guideline
1
Openfda Safety
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin E for Alzheimer's disease and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2012 PubMed DOI
A Exercise for intermittent claudication
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2021 PubMed DOI
A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis
Meta Analysis European journal of clinical nutrition 2023 PubMed DOI
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2022 PubMed DOI
View all evidence for Vitamin E →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.