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Melatonin 20 mg

product on market Capsule Progressive Professional from Progressive Laboratories Safety: 60/100
60/100

Review before taking

  • Melatonin: 20mg is 2.0× the Tolerable Upper Intake Level (10mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Melatonin is used to regulate sleep-wake cycles, with strong evidence supporting its efficacy for short-term insomnia and jet lag. However, the 20 mg dosage is significantly higher than typical clinical recommendations. This high concentration may lead to increased side effects, contributing to a lower safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Melatonin: 20mg is 2.0× the Tolerable Upper Intake Level (10mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 20mg of melatonin, which is twice the recommended upper limit of 10mg.

Label

Product Label

Label for Melatonin 20 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetable Capsule(s)
Serving Size
180
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

20 mg
Exceeds UL by 2.0× (UL: 10 mg) 240 studies (A:2, B:109)

Other Ingredients

Rice Flour L-Leucine Hydroxypropyl Methylcellulose
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Directions: One vegetable capsule daily, or more, as directed by health care professional.

Warnings & Precautions

Sold only for dispensing by a licensed health professional.

Pregnant and/or lactating women should consult their physician prior to use.

Tamper evident band around cap and seal on bottle. Do not use if either seal is broken or missing.

Keep out of the reach of children.

Formulation Notes

Contains no sugar, artificial flavors or preservatives.

Progressive Laboratories manufactured this product in its 3rd party GMP-inspected facility. (Good Manufacturing Practices)

Additional Information

GMP Good Manufacturing Practice Certified GMP Compliant 21 CFR 11

Metadata

Product Details

UPC / SKU3 51821 03721 9
DSLD Entry Date2022-04-11
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID261971
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Melatonin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.