🟡 60/100

Review before taking

  • Melatonin: 20mg is 2.0× the Tolerable Upper Intake Level (10mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Melatonin: 20mg is 2.0× the Tolerable Upper Intake Level (10mg)

This product received a low safety score because its 20mg dose of melatonin is double the recommended maximum daily limit of 10mg.

Label Data

1 Vegetable Capsule(s) Serving Size
180 Servings
Non-Nutrient/Non-Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

20 mg
⚠️ Exceeds Tolerable Upper Intake Level by 2.0× (UL: 10 mg) 📚 236 studies (Tier A: 2, B: 109)
This product: 20mg UL 10mg

Other Ingredients

Rice Flour L-Leucine Hydroxypropyl Methylcellulose

Label Claims — Verification

All Other
All Other (100% of products) Structure/Function (86% of products) Nutrient (7% of products)

Target Groups

Adult (18 - 50 Years) Sugar Free

Product Information

📋 Directions for Use

Directions: One vegetable capsule daily, or more, as directed by health care professional.

⚠️ Warnings & Precautions

Sold only for dispensing by a licensed health professional.

Pregnant and/or lactating women should consult their physician prior to use.

Tamper evident band around cap and seal on bottle. Do not use if either seal is broken or missing.

Keep out of the reach of children.

🧪 Formulation Notes

Contains no sugar, artificial flavors or preservatives.

Progressive Laboratories manufactured this product in its 3rd party GMP-inspected facility. (Good Manufacturing Practices)

Additional Information

GMP Good Manufacturing Practice Certified GMP Compliant 21 CFR 11

Product Details

UPC / SKU 3 51821 03721 9
DSLD Entry Date 2022-04-11
Product Type Non-Nutrient/Non-Botanical
Form Capsule
DSLD ID 261971
Data Updated 2026-04-11

Research Evidence

291 Research Sources
55 Avg Quality Score
129 Meta Analysis
93 Systematic Review
51 Rct
11 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021
View all evidence for Melatonin →

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