Berberine 1 g by XYMOGEN — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
100% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

2 Capsule(s) Serving Size

60 Servings

Non-Nutrient/Non-Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Berberine HCl

1 Gram(s)

📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)

This product: 1mg

Other Ingredients

Hypromellose Water Dicalcium Phosphate Ascorbyl Palmitate Silica

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (86% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take two capsules twice daily, or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Consult your healthcare professional before use.

Individuals taking medication should discuss potential interactions with their healthcare professional.

Do not use if tamper seal is damaged.

Storage: Keep closed in a cool, dry place out of reach of children.

🧪 Formulation Notes

Berberine is a naturally occurring plant alkaloid broadly used in traditional ayurvedic and Chinese herbal practices with demonstrated benefits for blood glucose and lipid metabolism. In addition, it is used to support gastrointestinal and immune health.

Formulated to exclude: Wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.

Berberine HCL 1 g

Vegetarian caps

Additional Information

Professional use only

Not for resale on third-party websites, including, but not limited to, Amazon and eBay.

Storage: Keep closed in a cool, dry place out of reach of children.

ePV

Exclusive professional formulas

Third-party verified GMP compliant

Scan to learn more!

This package is completely recyclable

Product Details

UPC / SKU 7 22537 51156 8

DSLD Entry Date 2022-01-22

Product Type Non-Nutrient/Non-Botanical

Form Capsule

Brand XYMOGEN

DSLD ID 258984

Data Updated 2026-04-11

Research Evidence

98 Research Sources

55 Avg Quality Score

48 Systematic Review

39 Meta Analysis

4 Rct

4 Clinical Trial

1 Other

1 Narrative Review

1 Openfda Safety

B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials

Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018

PubMed DOI

B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition ESPEN 2022

PubMed DOI

B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023

PubMed DOI

B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2019

PubMed DOI

B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials

Meta Analysis The Journal of nutrition 2023

PubMed DOI

B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review

Meta Analysis Journal of translational medicine 2024

PubMed DOI

B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature

Systematic Review International journal of molecular sciences 2024

PubMed DOI

B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials

Meta Analysis The American journal of Chinese medicine 2019

PubMed DOI

B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies

Meta Analysis International journal of molecular sciences 2023

PubMed DOI

B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial

Rct JAMA network open 2025

PubMed DOI

View all evidence for Berberine →