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Flush Free Niacin Inositol Hexanicotinate 500 mg

product on market Capsule CVS Pharmacy Safety: 80/100
80/100

This product is generally safe

  • Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Inositol hexanicotinate is a form of niacin used to support lipid profiles and cardiovascular health. Research evidence for this specific flush-free combination is limited compared to nicotinic acid. The ingredients are generally well-tolerated, though individual responses to niacin can vary.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Flush Free Niacin Inositol Hexanicotinate 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

400 mg (2000% DV)
Exceeds UL by 11.4× (UL: 35 mg) 196 studies (A:5, B:63)
100 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Gelatin Stearic Acid Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: For adults, take one (1) capsule daily, preferably with a meal.

Warnings & Precautions

As a reminder, discuss the supplements and medications you take with your health care providers.

KEEP OUT OF REACH OF CHILDREN.

TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.

WARNING: Not intended for use by pregnant or nursing women. If you are taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Do not take on an empty stomach.

Formulation Notes

No yeast, wheat, gluten, milk or milk derivatives, lactose, sugar, preservatives, soy artificial color, artificial flavor, salt.

Additional Information

HEART HEALTH

Supports Cardiovascular & Nervous System Health

STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.

Niacin is part of a coenzyme necessary for energy metabolism. It also maintains nervous system, heart and skin health.

NOTICE: Most people should not experience flushing when using this product. However, a few sensitive individuals may experience some flushing.

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ACTUAL SIZE

# 459949

Prod. No. 1664 B1660 02B

Metadata

Product Details

UPC / SKU0 50428 12861 9
DSLD Entry Date2013-09-25
Product TypeOther Combinations
FormCapsule
DSLD ID25895
Data Updated2026-04-11
Research

Research Evidence

32
Research Sources
50
Avg Quality
19
Rct
7
Meta Analysis
3
Clinical Trial
2
Other
1
Systematic Review
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024 PubMed DOI
B Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines
Meta Analysis The Journal of clinical endocrinology and metabolism 2024 PubMed DOI
B Antenatal dietary supplementation with myo-inositol for preventing gestational diabetes
Meta Analysis The Cochrane database of systematic reviews 2023 PubMed DOI
B Effectiveness of inositol, metformin and their combination in women with PCOS undergoing assisted reproduction: systematic review and meta-analysis
Meta Analysis Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2022 PubMed DOI
B Effects of myo-inositol vs. metformin on hormonal and metabolic parameters in women with PCOS: a meta-analysis
Meta Analysis Irish journal of medical science 2023 PubMed DOI
B Inositol for subfertile women with polycystic ovary syndrome
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
B Treatment of lean PCOS teenagers: a follow-up comparison between Myo-Inositol and oral contraceptives
Rct European review for medical and pharmacological sciences 2021 PubMed DOI
B The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios
Rct European review for medical and pharmacological sciences 2019 PubMed DOI
C Investigating the effect of combined use of selenium and Myo-inositol supplements on thyroid function and autoimmune characteristics in thyroid disorders: a systematic review and meta-analysis
Meta Analysis Expert review of endocrinology & metabolism 2024 PubMed DOI
C Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-controlled clinical trial.
Rct International journal of food sciences and nutrition PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.