🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
120 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Calcium
93 mg (7% DV)
10 mg
📊 Market median: 3.0mg (984 products) 📚 236 studies (Tier A: 2, B: 109)
This product: 10mg UL 10mg

Other Ingredients

Cellulose Maltodextrain Hydroxypropyl Methylcellulose Stearic Acid Magnesium Stearate Silicon Dioxide

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (86% of products) Nutrient (7% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, adults take one (1) tablet 30 minutes before bedtime or as directed by a healthcare provider. Do not exceed recommended dosage.

⚠️ Warnings & Precautions

Do not exceed recommended dosage.

Warning: Not intended for use by pregnant or nursing women or those under the age of 18. Consult a healthcare provider prior to use if you are taking medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur. Do not take if you plan to operate machinery, drive a vehicle or consume alcohol. Consult a healthcare provider if you experience consistent sleep difficulties or for extended use.

Warning: Not intended for use by pregnant or nursing women or those under the age of 18. Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

🧪 Formulation Notes

No added yeast, preservatives, artificial flavors or colors.

Prolonged release Sleep support

Gluten free

Melatonin works in harmony with your natural sleep cycle and promotes relaxation and sleep. Prolonged release vitamins slowly release nutrients into the body over an extended period of time.

Additional Information

Individual results may vary.

Store at room temperature.

New

Guaranteed quality Laboratory tested

Product Details

UPC / SKU 7 40985 28028 7
DSLD Entry Date 2022-01-22
Product Type Other Combinations
Form Tablet or Pill
Brand 21st Century
DSLD ID 258614
Data Updated 2026-04-11

Research Evidence

291 Research Sources
55 Avg Quality Score
129 Meta Analysis
93 Systematic Review
51 Rct
11 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021
View all evidence for Melatonin →

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