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Glucosamine HCl 1500 mg with MSM 1500 mg

product on market Tablet or Pill Kirkland Signature Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 25% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine HCl and MSM are commonly used to support joint health and cartilage maintenance. Research provides moderate evidence that these ingredients may reduce joint discomfort, though clinical results vary across populations. The overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Glucosamine HCl 1500 mg with MSM 1500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
187
Servings
Non-Nutrient/Non-Botanical
Product Type
25%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 {Calories}
Total Carbohydrates
2 grams (1% DV)
1500 mg
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
MSM
1500 mg
Market median: 1000.0mg (2 products)

Other Ingredients

Glucosamine Hydrochloride Methylsulfonylmethane Cellulose Contains <2% of:
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

SUGGESTED USE: Take two (2) tablets daily, or as directed by a physician.

Warnings & Precautions

CAUTION: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of the reach of children.

IMPORTANT: TAMPER-EVIDENT SEAL UNDER CAP. DO NOT USE IF PRINTED SEAL IS BROKEN OR MISSING.

Formulation Notes

No Preservative Added - No Lactose - No Artificial Color or Flavor - No Gluten

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

Additional Information

Quality Purity Potency

Glucosamine and MSM is a beneficial supplement combination that helps support maximum flexibility, range of motion and joint lubrication. Together, this powerful duo promotes healthy cartilage and collagen that support fluid joint movement.

Glucosamine is a basic component of cartilage and other connective tissues, which are needed for healthy structure and functions of joints. MSM (Methylsulfonylmethane), a bioavailable source of sulfur, is a necessary component that works in conjunction with Glucosamine to provide support for collagen, an important component of healthy joints and connective tissue. This product should be taken on a consistent basis to support joint health.

- Optimum JOINT HEALTH & MOBILITY - Helps support CARTILAGE

Actual Size

ITEM 249375

USP has tested and verified ingredients, potency, and manufacturing process. USP sets official standards for dietary supplement. See www.uspverified.org.

Tablet color may vary.

Store at room temperature, tightly closed. Avoid excessive heat.

Prod. No. 53184 B53191 06E

Two Tablets Per Day Deliver

EXTRA STRENGTH

UPS DIETARY SUPPLEMENT VERIFIED (R)

VITAMIN INFOLINE 1-800-433-1213

FRESHNESS AND POTENCY GUARANTEED THROUGH:

Metadata

Product Details

UPC / SKU0 96619 24937 4
DSLD Entry Date2013-09-25
Product TypeNon-Nutrient/Non-Botanical
FormTablet or Pill
DSLD ID25832
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.