5-HTP

product on market Capsule Lidtke Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-HTP serves as a precursor to serotonin and is researched for its role in supporting mood and sleep. There is moderate evidence suggesting it may help manage symptoms of depression, though overall evidence coverage for this specific profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
120
Servings
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

vegan Capsule Arrowroot Flour
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions (Adults): Take one (1) capsule two or three times per day with a beverage or meal, or as directed by your doctor.

Warnings & Precautions

Warning: Keep out of reach of children.

If you are pregnant, lactating, taking any medications (especially MAOIs, Tricyclics, or SSRIs), or have a medical condition, consult your doctor.

Discontinue use if adverse reaction occurs. Do not use if seal is damaged or missing.

Adverse events may be reported above.

Formulation Notes

Made with ultra-premium 5-HTP and meeting the highest standards, Lidtke 5-HTP is a natural building block of serotonin, the neurotransmitter that controls appetite, mood, normal sleep patterns, and nervous-system health.

Superb quality since 1994

5-Hydroxy L-Tryptophan

Calms nerves Relieves carb/sugar cravings Rapid release

Purest on the planet

No added gluten, yeast, wheat, corn, soy, rice, dairy, eggs, tree nuts, peanuts, fish, shellfish, sugar, artificial color or flavor, or preservatives. Non-GMO.

Additional Information

Thank you for choosing 5-HTP by Lidtke. We sincerely wish the best of health for you and your family.

Lidtke stands behind each product and guarantees customer satisfaction for 365 days from the date of purchase.

Keep lid tightly closed. Keep in a cool, dry place.

Metadata

Product Details

UPC / SKU6 30610 00323 0
DSLD Entry Date2021-11-19
Product TypeAmino acid/Protein
FormCapsule
BrandLidtke
DSLD ID257275
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.