🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
60 Servings
Botanical with Nutrients Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

6 mcg (250% DV)
✅ 2.5× RDA — within safe limits 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.006mg
Coffee
100 mg
Cognium Focus Blend
224 mg

Other Ingredients

Hypromellose Microcrystalline Cellulose Maltodextrin Magnesium Stearate Silicon Dioxide Dicalcium Phosphate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Dairy Free

Product Information

📋 Directions for Use

Directions: Take 1 capsule daily with or without food. Do not exceed 3 capsules.

⚠️ Warnings & Precautions

Warning: Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking prescription drugs, or are pregnant or lactating.

Each serving contains as much caffeine as about 2 cups of coffee. Limit the use of caffeine containing medication, foods or beverages while taking this product. Too much caffeine may cause nervousness, irritability, sleeplessness and occasionally rapid heartbeat. This product is not intended/recommended for children and those sensitive to caffeine.

Contains: Soy

Keep out of reach of children.

This product contains 120 mg of naturally occurring caffeine.

Not recommended for children, pregnant or lactating women and persons sensitive to caffeine.

Not recommended for children, pregnant or lactating women and persons sensitive to caffeine.

🧪 Formulation Notes

Vegetarian

Brain Health Improves focus & concentration

No: Milk, egg, fish, crustacean shellfish. tree nuts, peanuts, wheat, yeast, artificial colors or flavors, added sugar or preservatives.

Additional Information

Store in a cool, dry place.

Product Details

UPC / SKU 0 47469 07633 7
DSLD Entry Date 2021-10-22
Product Type Botanical with Nutrients
Form Capsule
Brand Natrol
DSLD ID 256968
Data Updated 2026-04-11

Research Evidence

237 Research Sources
53 Avg Quality Score
83 Meta Analysis
74 Systematic Review
45 Rct
29 Clinical Trial
2 Guideline
2 Regulatory Source
1 Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023
View all evidence for Vitamin B12 →

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