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Berberine-500+ TripleDefense

product on market Capsule Wonder Labs Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Berberine and cinnamon are supported by moderate to strong evidence for assisting in the management of blood glucose levels. Chromium further complements this profile by supporting insulin sensitivity. Together, these ingredients target metabolic health through various biochemical pathways.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Berberine-500+ TripleDefense
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

72 mcg (60% DV)
2.1× RDA — within safe limits 199 studies (A:1, B:55)
500 mg
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
Cinnamon
334 mg

Other Ingredients

Gelatin Vegetable Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take 3 capsules daily, one before each meal.

Warnings & Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing. Keep tightly closed.

Keep out of reach of children.

Warning: Diabetics/Hypoglycemics use only under a doctor's supervision because this product contains chromium which may enhance insulin sensitivity and may affect your blood sugar.

If you are pregnant or nursing do not take this product.

Formulation Notes

USA Made

Berberine Cinnamon Chromium

Nutritionally supports healthy blood sugar and cholesterol levels that are already within normal range

Glucose Metabolism - Weight loss support Support immune function Supports detoxification

Additional Information

Store at room temperature: 59 degrees-86 degrees F (15 degrees-30 degrees C).

FDA Registered Facility

GMP Certified Good Manufacturing Practice

Metadata

Product Details

DSLD Entry Date2021-10-22
Product TypeOther Combinations
FormCapsule
BrandWonder Labs
DSLD ID256055
Data Updated2026-04-11
Research

Research Evidence

98
Research Sources
55
Avg Quality
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019 PubMed DOI
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023 PubMed DOI
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024 PubMed DOI
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025 PubMed DOI
View all evidence for Berberine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.