🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
60 Servings
Non-Nutrient/Non-Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

500 mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 500mg

Other Ingredients

Gelatin Cellulose Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (86% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Suggested Use: When used as a supplement, take 2-4 500 mg capsules per day, divided into three or four total doses. It is not recommended that more than 1 capsule be taken at one time, as taking too much Berberine at once can cause adverse side effects. Berberine should be taken along with, or directly after a meal in order to maximize it's beneficial impact on blood glucose levels.

⚠️ Warnings & Precautions

Warning: Consult your physician before taking this product. Do not consume more than 4 capsules per day.

Do not take this product if you are pregnant, nursing or taking any other medications.

Discontinue use and consult your doctor immediately if any adverse reactions occur.

Do not take Berberine and operate any heavy machinery until you know how it affects you.

Keep out of reach of children.

🧪 Formulation Notes

Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. It is found in a wide variety of plants including goldenseal, yellowroot, and prickly poppy. When taken as a supplement it provides a wide array of health benefits including managing blood glucose levels, lowering cholesterol, supporting cardiovascular health, and is neuroprotective.

Supports cardiovascular & mental health Helps manage blood glucose levels

Additional Information

Storage: Store in a cool, dark place. Do not freeze or expose to moisture or heat above room temperature.

Product Details

UPC / SKU 7 26670 11400 6
DSLD Entry Date 2021-09-24
Product Type Non-Nutrient/Non-Botanical
Form Capsule
DSLD ID 255568
Data Updated 2026-04-11

Research Evidence

98 Research Sources
55 Avg Quality Score
48 Systematic Review
39 Meta Analysis
4 Rct
4 Clinical Trial
1 Other
1 Narrative Review
1 Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025
View all evidence for Berberine →

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