5-HTP 100 mg

product on market Capsule Patient One 1 MediNutritionals 🟢 Safety: 100/100
Brand: Patient One 1 MediNutritionals
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
60 Servings
Amino acid/Protein Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

100 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 100mg

Other Ingredients

Rice Flour Vegetable Cellulose Stearic Acid Leucine Silica

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested use: Take 1 capsule 1 to 2 times daily in divided doses between meals, as a dietary supplement or as directed by your health practitioner. To derive optimal benefits of 5-HTP, ensure adequate intake of Vitamin B6.

⚠️ Warnings & Precautions

Caution: Consult your health practitioner before use. Do not use concurrently with SSRI medications, MAO inhibitors or other antidepressant medication. Not recommended if pregnant or nursing or for children under age 12.

Not recommended if pregnant or nursing or for children under age 12.

Discontinue use and consult your health practitioner if any adverse reactions occur.

Keep out of reach of children.

🧪 Formulation Notes

Vegetarian

Gluten free Non-GMO

Free of: Milk, egg, fish, peanuts, crustacean shellfish, soy, tree nuts, wheat, yeast and gluten. Free of ingredients derived from GMOs.

Additional Information

Store in a cool, dry place.

Exclusive Professional Formulas

BPA free

Product Details

UPC / SKU 8 59782 00624 9
DSLD Entry Date 2021-04-22
Product Type Amino acid/Protein
Form Capsule
Brand Patient One 1 MediNutritionals
DSLD ID 249113
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
PubMed Cochrane
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
PubMed Cochrane
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
PubMed DOI
View all evidence for 5 Htp →

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