Immune Vitamin D3 5000 IU (125 mcg)

product on market Softgel Capsule NaturesPlus 🟡 Safety: 60/100
Brand: NaturesPlus
🟡 60/100

Review before taking

  • Vitamin D3: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

Vitamin D3 is supported by strong evidence for maintaining bone health and supporting immune function. However, the high dosage of 5000 IU may lead to safety concerns regarding toxicity or hypercalcemia in some individuals. Consult a professional to ensure this level is appropriate for your needs.

AI-generated summary based on research evidence. Not medical advice.

Product Label

Label for Immune Vitamin D3 5000 IU (125 mcg)
📄 Open Full PDF View on NIH DSLD →
📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Safety Alerts

⚠️ Vitamin D3: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)

This product received a low safety score because it contains more Vitamin D3 than the recommended daily upper limit. Specifically, the dose is 1.2 times higher than the maximum amount generally considered safe for daily intake.

Label Data

1 Softgel(s) Serving Size
60 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

125 mcg (625% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.2× (UL: 0.1 mg) 📚 608 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.125mg UL 0.1mg

Other Ingredients

EFASorb Gelatin Safflower Oil Vegetable Glycerin Beeswax purified Water Turmeric extract

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (70% of products) Approved Health (4% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Can be taken with other NaturesPlus Immune Formulas.

Directions: As a dietary supplement, take one softgel daily.

⚠️ Warnings & Precautions

Keep out of the reach of children.

🧪 Formulation Notes

Vitamin D3 is essential for a strong, healthy immune response. NaturesPlus Immune Vitamin D3 5000 IU achieves unmatched absorption, using MicroParticle Emulsion, which ensures optimally micronized D3 nutrient particles. EFASorb blend (a specialized nutrient complex) further boosts uptake in the gut. The result is maximized effectiveness with high-potency NaturesPlus Immune Vitamin D3 5000 IU.

Emulsified for maximum absorption

Free from artificial colors, artificial preservatives and all of the major allergens identified in the U.S. Food Allergen Labeling and Consumer Protection Act. Gluten free

Additional Information

Optimize your immune health and overall well-being!

Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 0 97467 41004 6
DSLD Entry Date 2021-06-23
Product Type Vitamin
Form Softgel Capsule
Brand NaturesPlus
DSLD ID 248827
Data Updated 2026-04-11

Research Evidence

872 Research Sources
53 Avg Quality Score
309 Meta Analysis
309 Clinical Trial
111 Rct
71 Systematic Review
55 Guideline
4 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
2 Observational
1 Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI Cochrane
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI Cochrane
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI Cochrane
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI Cochrane
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011
PubMed DOI Cochrane
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023
PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023
PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI
View all evidence for Vitamin D →

Compare Similar Products

Vitamin D 2000 IU
Vitamin D 2000 IU Viva Vitamins 100
Vitamin D 1,000 IU
Vitamin D 1,000 IU Vitamer Laboratories 100
Vitamin D3 1000 IU
Vitamin D3 1000 IU VitaCeutical Labs 100
Vitamin D3 2,000 IU
Vitamin D3 2,000 IU VitaCeutical Labs 100
Vitamin D3 400 IU
Vitamin D3 400 IU VitaCeutical Labs 100
View all Vitamin D products →
Vitamin D research & evidence Best Vitamin D rankings All Vitamin D products More from NaturesPlus View on NIH DSLD →