🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Vegetable Capsule(s) Serving Size
90 Servings
Other Combinations Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

50 mg (2500% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
200 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 200mg

Other Ingredients

Vegetable Capsule

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Kosher Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take 1 capsule 1-2 times a day or as directed by your physician.

⚠️ Warnings & Precautions

Warning: Not intended for use by persons under the age of 18. Keep out of the reach of children.

If you are pregnant, breast feeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.

Discontinue use two weeks prior to surgery.

🧪 Formulation Notes

Vegetarian

Gluten free Non-GMO Lactose free No excipients, no fillers, allergen free, no artificial color, flavor or sweetener, no preservatives, no starch, no sugar, no soy, no wheat, no yeast, no fish, no milk, sodium free.

Manufactured in our GMP & FDA inspected facility FDA Registration: 16906175560

5-Hydroxytryptophan

Supports positive mood & restful sleep

OU (Kosher)

Full label transparency

Additional Information

Since 1996

Made in USA with ingredients sourced worldwide

OU (Kosher)

Store in a cool dry place.

Product Details

UPC / SKU 6 49908 27006 3
DSLD Entry Date 2021-04-22
Product Type Other Combinations
Form Capsule
Brand NutraBio
DSLD ID 248182
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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