🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Capsule(s) Serving Size
180 Servings
Amino acid/Protein Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 100mg

Other Ingredients

Gelatin Rice powder

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: For adults, take one (1) capsule twice daily as needed or before bedtime.

⚠️ Warnings & Precautions

Keep out of reach of children.

Warning: Not for use by pregnant or lactating women. Avoid this product if you are taking antidepressants or weight-control drugs.

May cause drowsiness. Do not drive a motor vehicle or operate heavy machinery or equipment while using this product. Do not exceed recommended dose. Excessive intake may cause adverse reactions.

Consult your doctor before use if you have or have had, any health condition or if you are taking any medications or remedies including OTC medications, or are planning any medical procedure.

Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or headache.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Tamper Resistant: Do not use if seal under cap is broken.

🧪 Formulation Notes

5-Hydroxytryptophan

Supports Nervous System Health

Contains No: Artificial coloring, artificial flavor preservatives, yeast, corn, milk, or milk derivatives. lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

Guaranteed Laboratory Tested Quality

Additional Information

Premium Brand / Optimum Results

Store in a dry place and avoid excessive heat.

We have assayed & fully guarantee the quality & potency of this product.

Manufactured in a FDA registered facility that conforms to GMP standards GMP Good Manufacturing Practice Consistent Quality

Made in the USA

100% Satisfaction Guaranteed

Store in a dry place and avoid excessive heat.

We have assayed & fully guarantee the quality & potency of this product.

Product Details

UPC / SKU 7 13807 37516 4
DSLD Entry Date 2021-04-22
Product Type Amino acid/Protein
Form Capsule
DSLD ID 247580
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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