🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
Other Combinations Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

3 mg (150% DV)
✅ 2.3× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 3mg UL 100mg
50 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 50mg
Glycine
220 mg

Other Ingredients

vegetarian capsule

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DIRECTIONS: One (1) capsule daily as a dietary supplement, or as directed by a Doctor. Best taken between meals or at bedtime.

⚠️ Warnings & Precautions

KEEP OUT OF THE REACH OF CHILDREN.

CAUTION: Do not take with MAO inhibitors or tricyclic antidepressants.

Pregnant or lactating women, consult your healthcare professional before taking this product.

🧪 Formulation Notes

Excipient-free.

Additional Information

Each preservative-free vegetarian capsule contains only the active ingredients listed on the label.

STORAGE: Keep tightly closed in a dry place; do not expose to excessive heat.

11144B EXP 11/12

Manufactured in a GMP Certified Facility

v.11

Product Details

UPC / SKU 8 38287 00100 3
DSLD Entry Date 2013-08-23
Product Type Other Combinations
Form Capsule
DSLD ID 24703
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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