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No-Flush Niacin 525 mg Inositol Hexanicotinate

product on market Capsule Natural Nutra Safety: 80/100
80/100

This product is generally safe

  • Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Inositol hexanicotinate provides a non-flushing form of niacin, which is used to support cholesterol levels and cardiovascular health. Research evidence for this specific compound is limited compared to nicotinic acid. Both ingredients are generally well-tolerated, though individual responses to niacin may vary.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for No-Flush Niacin 525 mg Inositol Hexanicotinate
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
100
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

400 mg (2500% DV)
Exceeds UL by 11.4× (UL: 35 mg) 196 studies (A:5, B:63)
110 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Vegetarian Capsule Cellulose Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take one capsule up to four times daily with meals.

Warnings & Precautions

Keep out of reach of children.

Formulation Notes

Contains no artificial colors, flavors or preservatives; no wheat, gluten, milk, eggs, peanuts, tree nuts, soy, crustacean shellfish or fish.

Suitable for vegans.

Niacin has long been a popular supplement used for healthy cholesterol support, but many users often complain about the "niacin flush" that accompanies its use. Our vegetarian formula No-Flush Niacin, also known as inositol hexanicotinate, is a form of niacin that provides all of the same benefits as traditional niacin without the flush. This is possible because the body metabolizes inositol hexanicotinate slower than traditional niacin, not reaching full serum levels for nearly 10 hours. Purity + potency guaranteed

Cholesterol support

Gluten free

Vegan

Additional Information

To report a serious adverse event, call 1-888-710-0006

Metadata

Product Details

DSLD Entry Date2021-04-22
Product TypeOther Combinations
FormCapsule
DSLD ID247021
Data Updated2026-04-11
Research

Research Evidence

32
Research Sources
50
Avg Quality
19
Rct
7
Meta Analysis
3
Clinical Trial
2
Other
1
Systematic Review
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024 PubMed DOI
B Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines
Meta Analysis The Journal of clinical endocrinology and metabolism 2024 PubMed DOI
B Antenatal dietary supplementation with myo-inositol for preventing gestational diabetes
Meta Analysis The Cochrane database of systematic reviews 2023 PubMed DOI
B Effectiveness of inositol, metformin and their combination in women with PCOS undergoing assisted reproduction: systematic review and meta-analysis
Meta Analysis Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2022 PubMed DOI
B Effects of myo-inositol vs. metformin on hormonal and metabolic parameters in women with PCOS: a meta-analysis
Meta Analysis Irish journal of medical science 2023 PubMed DOI
B Inositol for subfertile women with polycystic ovary syndrome
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
B Treatment of lean PCOS teenagers: a follow-up comparison between Myo-Inositol and oral contraceptives
Rct European review for medical and pharmacological sciences 2021 PubMed DOI
B The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios
Rct European review for medical and pharmacological sciences 2019 PubMed DOI
C Investigating the effect of combined use of selenium and Myo-inositol supplements on thyroid function and autoimmune characteristics in thyroid disorders: a systematic review and meta-analysis
Meta Analysis Expert review of endocrinology & metabolism 2024 PubMed DOI
C Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-controlled clinical trial.
Rct International journal of food sciences and nutrition PubMed DOI
View all evidence for Inositol →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.