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MigraPlex

product on market Capsule Karuna Safety: 80/100
80/100

This product is generally safe

  • Magnesium: 600mg is 1.7× the Tolerable Upper Intake Level (350mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Magnesium and feverfew are used to support the management of migraines, with moderate evidence suggesting they may reduce frequency and severity. However, overall evidence coverage for this specific formulation is limited. The profile maintains a high safety score, indicating a generally low risk of adverse effects.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 600mg is 1.7× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for MigraPlex
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

600 mg (150% DV)
Exceeds UL by 1.7× (UL: 350 mg) 316 studies (A:8, B:159)
100 mg
Market median: 380.0mg (120 products) 8 studies — no high-quality reviews

Other Ingredients

Vegetable Stearate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested use for adults: One (1) capsule, with meals, three times daily, or as directed by your health care practitioner.

Warnings & Precautions

Caution: This product is not recommended for pregnant or lactating women.

Formulation Notes

Whole Leaf Feverfew with Magnesium

This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.

Additional Information

L911035E01/13

KARUNA(R) RESPONSIBLE NUTRITION(TM)

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

Keep in a cool, dry place, tightly capped.

9140-LB1

Metadata

Product Details

DSLD Entry Date2013-08-23
Product TypeOther Combinations
FormCapsule
BrandKaruna
DSLD ID24674
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.