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Melatonin

product on market Capsule Karuna Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Melatonin is a hormone that regulates sleep-wake cycles and is supported by strong evidence for reducing sleep onset latency. Research indicates it is effective for managing jet lag and certain circadian rhythm disorders. The ingredient profile is generally recognized as safe for short-term use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Melatonin
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

vegetarian capsule Rice Flour
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested use for adults: One capsule daily taken 1 hour before bedtime, or as directed by your health care practitioner.

Warnings & Precautions

Caution: Not for use by individuals under the age of 18 years or for pregnant or lactating women.

Caution: Not for use by individuals under the age of 18 years or for pregnant or lactating women.

Additional Information

KARUNA(R) RESPONSIBLE NUTRITION(TM)

Natural Support for Body Rhythms and Normal Sleep

6107-LB5

Metadata

Product Details

UPC / SKU0 18647 08107 8
DSLD Entry Date2013-08-23
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandKaruna
DSLD ID24661
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Melatonin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.