Home/ Supplements/ Melatonin/ Melatonin P.R. 3 mg Prolonged-Release

Melatonin P.R. 3 mg Prolonged-Release

product on market Tablet or Pill Douglas Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Melatonin is a hormone that regulates sleep-wake cycles and is supported by strong evidence for reducing sleep onset latency. This prolonged-release formulation is designed to maintain levels throughout the night to improve sleep maintenance. Research indicates the ingredient is generally well-tolerated for short-term use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Melatonin P.R. 3 mg Prolonged-Release
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
180
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Ethylcellulose Stearic Acid Vegetable Stearate Coating Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: As a dietary supplement, adults take 1 tablet 1 hour before bedtime as directed by your health professional only.

Warnings & Precautions

Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health professional before using this product. Consult a health professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication.

Consult a health professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication.

Consult a health professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication. Do not drive or operate machinery when taking melatonin.

Keep out of the reach of children.

Use only if safety seal is intact.

Formulation Notes

Gluten-free, Non-GMO

Support for restful sleep

Additional Information

Store in a cool, dry place.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our manufacturing excellence

Metadata

Product Details

UPC / SKU3 10539 01782 1
DSLD Entry Date2021-02-25
Product TypeNon-Nutrient/Non-Botanical
FormTablet or Pill
DSLD ID245312
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.