Sleep Regimen 3-in-1

product on market Capsule NOW 🟢 Safety: 100/100
Brand: NOW
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Veg Capsule(s) Serving Size
Other Combinations Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

200 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 200mg
50 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 50mg
3 mg
📊 Market median: 3.0mg (984 products) 📚 236 studies (Tier A: 2, B: 109)
This product: 3mg UL 10mg

Other Ingredients

Hypromellose Microcrystalline Cellulose Stearic Acid Silicon Dioxide

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (92% of products) Nutrient (22% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested usage: Take 1 capsule about 1 hour before bedtime with juice or water.

May cause drowsiness and mild transient GI symptoms. Take with food in case of GI upset.

⚠️ Warnings & Precautions

Caution: For adults only.

Not recommended for pregnant/nursing women.

Do not operate a vehicle or heavy machinery following consumption of melatonin.

Consult physician if taking medications (especially sedatives, immunosuppressants, anticoagulants, antidepressants, blood pressure medications), or have a medical condition.

May cause drowsiness and mild transient GI symptoms. Take with food in case of GI upset.

Keep out of reach of children.

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that process other ingredients containing these allergens.

🧪 Formulation Notes

NOW Sleep Regimen 3-in-1 is formulated to relax the mind and promote restful sleep. This formula encourages relaxation and has melatonin to support the regulation of the body's sleep/wake cycle. 5-HTP has been included to support serotonin production, which promotes a sense of calm. Altogether, this product can help you wind down at the end of the day and get a good night's sleep.

Restful sleep blend

Promotes relaxation

with melatonin & 5-HTP

Non-GMO

Vegetarian/vegan

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

Additional Information

General health Family owned since 1968.

Store in a cool, dry place after opening.

Product Details

UPC / SKU 7 33739 04769 4
DSLD Entry Date 2021-04-22
Product Type Other Combinations
Form Capsule
Brand NOW
DSLD ID 244780
Data Updated 2026-04-11

Research Evidence

37 Research Sources
53 Avg Quality Score
22 Rct
10 Systematic Review
3 Meta Analysis
1 Clinical Trial
1 Openfda Safety
B Examining the effect of L-theanine on sleep: a systematic review of dietary supplementation trials
Systematic Review Nutritional neuroscience 2026
PubMed DOI
B The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis
Meta Analysis Sleep medicine reviews 2025
PubMed DOI
B The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness
Rct Nutritional neuroscience 2010
PubMed DOI
B Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial
Rct Nutrients 2019
PubMed DOI
B The Role of Supplements and Over-the-Counter Products to Improve Sleep in Children: A Systematic Review
Systematic Review International journal of molecular sciences 2023
PubMed DOI
B Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrition reviews 2025
PubMed DOI
B Effect of Alpha-S1-Casein Tryptic Hydrolysate and L-Theanine on Poor Sleep Quality: A Double Blind, Randomized Placebo-Controlled Crossover Trial
Rct Nutrients 2022
PubMed DOI
B Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study
Rct Nutritional neuroscience 2025
PubMed DOI
B The combined effects of L-theanine and caffeine on cognitive performance and mood
Rct Nutritional neuroscience 2008
PubMed DOI
B Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2014
PubMed DOI
View all evidence for L Theanine →

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