Home/ Supplements/ Vitamin E/ E-400

E-400

product on market Softgel Capsule Karuna Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Natural Vitamin E serves as an antioxidant that helps protect cells from oxidative stress. Research provides strong evidence for its role in supporting immune function and skin health. However, overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for E-400
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel Capsule(s)
Serving Size
90
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

400 IU (1333% DV)
17.9× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)

Other Ingredients

Gelatin Glycerine Soybean Oil
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested use for adults: 1-2 capsules daily, taken with meals, or as directed by your health care practitioner.

Formulation Notes

This product contains no yeast, milk or milk derivatives, lactose, sugar, preservatives, artificial color or flavor.

Natural Unesterified Vitamin E

Additional Information

KARUNA(R) RESPONSIBLE NUTRITION(TM)

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

Keep in a cool, dry place, tightly capped.

1205-LB6

Metadata

Product Details

UPC / SKU0 18647 01205 8
DSLD Entry Date2013-08-23
Product TypeVitamin
FormSoftgel Capsule
BrandKaruna
DSLD ID24367
Data Updated2026-04-11
Research

Research Evidence

253
Research Sources
55
Avg Quality
128
Meta Analysis
52
Systematic Review
41
Rct
24
Clinical Trial
3
Regulatory Source
1
Narrative Review
1
Other
1
Guideline
1
Openfda Safety
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin E for Alzheimer's disease and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2012 PubMed DOI
A Exercise for intermittent claudication
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2021 PubMed DOI
A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis
Meta Analysis European journal of clinical nutrition 2023 PubMed DOI
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2022 PubMed DOI
View all evidence for Vitamin E →
Compare

Similar Products

Vitamin E 1000 IU
Sundown Naturals · Softgel Capsule
100
100% Natural E-1000 IU
Vitamin World · Softgel Capsule
100
Ester-E 400 IU
Vitamin World · Softgel Capsule
100
Natural VItamin E 400 IU
Country Life · Softgel Capsule
100
Healthy Heart Essentials
SeniorLife Health · Softgel Capsule
100
View all Vitamin E products →
Vitamin E research Best Vitamin E All Vitamin E products More from Karuna View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.