🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Caplet(s) Serving Size
30 Servings
Botanical Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 600mg
📊 Market median: 375.0mg (171 products) 📚 30 studies (Tier A: 1, B: 14)
This product: 100mg
Black Pepper fruit extract
20 mg

Other Ingredients

Cellulose Croscarmellose Sodium Stearic Acid Calcium Silicate Silicon Dioxide Magnesium Stearate Triacetin Polyethylene Glycol Oleic Acid Di-Acetylated Monoglycerides

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (7% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take one caplet twice daily.

⚠️ Warnings & Precautions

Keep out of reach of children.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

🧪 Formulation Notes

ApresFlex supports a 7 times greater improvement in joint control In a 30 day, randomized, double-blind, placebo-controlled study of 67 adults, subjects taking 50 mg of ApresFlex twice daily experienced a statistically significant difference in mean improvements from baseline for joint comfort, stiffness and function as measured by WOMAC that was 7,5 and 43 times greater in the ApresFlex group than placebo, respectively, after 30 days. Statistically significant improvements were seen as early as 5 days.

TriFlex Turmeric Formula is a vegetarian, shellfish free solution with clinically proven ApresFlex for joint health.

Herbal - Unlike most joint care products, TriFlex Turmeric Formula doesn't contain glucosamine or chondroitin, so it's perfect for those who are allergic to shellfish or prefer a vegetarian solution.

Fast Acting - Features ApresFlex, a potent boswellia serrata extract, which is clinically proven to support a 7 times greater improvement in joint comfort, as well as improvements in joint stiffness and function, in as few as 5 days. It is thought to work by targeting pathways related to your body's natural anti-inflammatory response. Highly Absorbable- Includes CurcuWIN Turmeric, which is clinically proven to have superior absorbability. Turmeric has traditionally been used to support joint health.

Vegetarian

Shellfish-Free

Herbal joint support Improves joint comfort & stiffness in as few as 5 days Promotes mobility & flexibility

Conforms to USP <2091> for weight.

No sugar, no starch, no artificial colors, no artificial flavors, no preservatives, no wheat, gluten free, no corn, no soy, no dairy, yeast free.

Additional Information

Store in a cool, dry place.

Our quality commitment to you Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you are not 100% satisfied with your purchase, return the unused portion of the product with your receipt within 30 days, and we'll either refund your money or find a replacement product that is right for you.

Feel better and get moving - fast! New!

Product Details

DSLD Entry Date 2021-02-25
Product Type Botanical
Form Other (e.g. tea bag)
Brand GNC
DSLD ID 243618
Data Updated 2026-04-11

Research Evidence

311 Research Sources
54 Avg Quality Score
121 Systematic Review
98 Meta Analysis
70 Rct
16 Clinical Trial
2 Other
1 Narrative Review
1 Openfda Safety
A The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis
Meta Analysis Bioscience reports 2021
B Curcumin for depression: a meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2020
B Effect of Aromatic Herbs and Spices Present in the Mediterranean Diet on the Glycemic Profile in Type 2 Diabetes Subjects: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2024
B Complementary and Alternative Medicine Therapies for Psoriasis: A Systematic Review
Meta Analysis JAMA dermatology 2018
B Functional foods modulating inflammation and metabolism in chronic diseases: a systematic review
Systematic Review Critical reviews in food science and nutrition 2022
B Effect of curcumin supplementation on symptoms of anxiety: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2024
B The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis
Meta Analysis Complementary therapies in medicine 2021
B Efficacy of Curcumin-Mediated Antimicrobial Photodynamic Therapy on Candida spp.-A Systematic Review
Systematic Review International journal of molecular sciences 2024
B Effects of curcumin on serum inflammatory biomarkers in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis BMC complementary medicine and therapies 2025
B Natural Products in Alzheimer's Disease: A Systematic Review of Clinical Trials and Underlying Molecular Mechanisms
Systematic Review International journal of molecular sciences 2025
View all evidence for Curcumin →

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