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Oregon Grape 500 mg

product on market Capsule Nature's Way Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Oregon grape contains berberine, which has been studied for its potential to support healthy inflammatory responses and blood sugar levels. Current research evidence for these effects is limited. The ingredient profile is generally considered safe for most users.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Oregon Grape 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)

Other Ingredients

plant-derived Capsule Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Take 1 capsule three times daily.

Warnings & Precautions

Warning: Do not use this product if you are pregnant or nursing. If you have diabetes or are taking any medications, consult a healthcare professional before use.

Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

Formulation Notes

Traditional digestive support

Non GMO Project Verified nongmoproject.org

Gluten free. No wheat, soy, corn, dairy, yeast-derived ingredients, or artificial colors, flavors, or preservatives.

Vegan

Oregon Grape 500 mg per serving

Additional Information

At Nature's Way, we believe in quality you can trust. So, we start by sourcing botanicals from the places they grow best. Then we use three distinct levels of scientific testing methods to ensure ingredients meet our uncompromising standards. Look for the TRU-ID logo to find products certified for authenticity by independent, third-party testing.

Nature’s Way since 1969

Certified Authentic TRU-ID Non GMO Project Verified nongmoproject.org

Bottles made from 97% post-consumer recycled plastic

Bottled & tested in the USA Quality Global Sourcing

Metadata

Product Details

UPC / SKU0 33674 14159 5
DSLD Entry Date2021-04-22
Product TypeBotanical
FormCapsule
BrandNature's Way
DSLD ID243044
Data Updated2026-04-11
Research

Research Evidence

98
Research Sources
55
Avg Quality
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019 PubMed DOI
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023 PubMed DOI
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024 PubMed DOI
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025 PubMed DOI
View all evidence for Berberine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.