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Osteo Bi-Flex Ease

product on market Tablet or Pill Osteo Bi-Flex Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains UC-II and Boswellia serrata, which have moderate evidence for supporting joint function and reducing inflammation. Vitamin D supports bone health and calcium absorption. Research indicates these ingredients are generally well-tolerated, aligning with the product's high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Osteo Bi-Flex Ease
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mcg (50% DV)
Within RDA (0.7× RDA) 608 studies (A:16, B:251)
Market median: 375.0mg (171 products) 31 studies (A:1, B:14)
UC-II standardized Cartilage
40 mg

Other Ingredients

Calcium Carbonate Cellulose Cellulose Coating Stearic Acid Croscarmellose Polydextrose Titanium Dioxide color Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

1 per day

Directions For Adult Use: Take one (1) tablet per day preferably with food.

Warnings & Precautions

Keep out of reach of children.

Tamper Resistant: Do not use if blister seal is cut, torn or open.

Caution: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18.

As a reminder, discuss the supplements and medications you take with your health care providers.

Formulation Notes

Joint Health

UC-ll Collagen a unique natural source of collagen that supports joint comfort. Joint Shield 5-Loxin Advanced shows Improved Joint Comfort in 7 Days. Vitamin D3 an active & potent form of Vitamin D that helps support bone health.

Helps to: Support joint function Support joint mobility

Made to Move During the day, you move your joints in so many different ways, getting up, sitting down, bending and flexing. Osteo Bi-Flex is America's #1 Joint Health brand and supports joint comfort, so you can enjoy a range of motion for your day's activities.

Start feeling the difference in your joints in just 7 days with the power of Joint Shield! Osteo Bi-Flex is manufactured under the highest standards for product quality, purity and potency.

Joint health Shows improved joint comfort within 7 days!

UC-II collagen with Joint Shield

Free of gluten and shellfish Non-GMO

Made in the USA with select ingredients from around the world.

Advanced Triple Action

Additional Information

#1 Pharmacist recommended brand 2020-2021 U.S.News & World Report Pharmacy Times

Enjoy a Range of Motion with Osteo Bi-Flex Ease! Say goodbye to traditional joint formulas and hello to Osteo Bi-Flex Ease.

To learn more about Osteo Bi-Flex visit www.osteobiflex.com or call us toll free 1-888-vitahelp (848-2435).

Store at room temperature and avoid excessive heat.

See bottom of box for more information about our Ambassador’s Club

#1 Pharmacist recommended brand

80% smaller tablet

20 points Join the Ambassador’s Club for rewards Visit www.osteobiflex.com for more information.

Compared to Osteo Bi-Flex One Per Day tablet. Based on the results of the Pharmacy Times Survey of Pharmacists' OTC Recommendations who recommend a “joint health” dietary supplement, (2020-2021).

Based on two human studies with 5-Loxin Advanced where subjects rated their joint health over time, subjects’ joint health improved within 7 days, and continued to improve throughout the duration of the studies. Source IRI Total US - Multi Outlet: Latest 52 week ending April 26, 2020.

Metadata

Product Details

UPC / SKU0 30768 55388 3
DSLD Entry Date2021-03-25
Product TypeOther Combinations
FormTablet or Pill
DSLD ID242703
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.