Home/ Supplements/ Melatonin/ Melatonin P.R. Prolonged-Release 3 mg

Melatonin P.R. Prolonged-Release 3 mg

product on market Tablet or Pill Douglas Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Melatonin is a hormone used to regulate sleep-wake cycles, with strong evidence supporting its efficacy for short-term sleep onset issues. This prolonged-release formulation is designed to maintain levels over a longer period. Research indicates it is generally well-tolerated for temporary use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Melatonin P.R. Prolonged-Release 3 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
60
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Ethylcellulose Stearic Acid Vegetable Stearate Coating Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: As a dietary supplement, adults take 1 tablet 1 hour before bedtime as directed by your healthcare professional only.

Warnings & Precautions

Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health professional before using this product. Consult a health professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication. Do not drive or operate machinery when taking melatonin. This product may be contraindicated for individuals taking corticosteroids.

Consult a health professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication. Keep out of the reach of children.

Use only if safety seal is intact.

Formulation Notes

Gluten-free, Non-GMO

Support for restful sleep

Additional Information

Store in a cool, dry place.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our manufacturing excellence

Metadata

Product Details

UPC / SKU3 10539 00518 7
DSLD Entry Date2020-08-23
Product TypeNon-Nutrient/Non-Botanical
FormTablet or Pill
DSLD ID232188
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.