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Creatine Monohydrate

product on market Powder Nootropics Depot Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Creatine monohydrate is supported by strong evidence for increasing muscle mass and improving strength during high-intensity exercise. Research indicates it works by increasing phosphocreatine stores to enhance ATP production in muscles. This ingredient is widely recognized as safe for most healthy adults.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Creatine Monohydrate
Open Full PDF View on NIH DSLD →
Details

Label Data

5 Gram(s)
Serving Size
100
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 5.0mg (298 products) 705 studies (A:5, B:123)
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, take 5000mg once daily.

Warnings & Precautions

Disclaimer: Always consult with a qualified health physician before taking any new dietary supplement.

Warning: Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).

Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).

Additional Information

Transfer scoops are not accurate forms of measurement. A milligram scale is needed to accurately measure dosages.

Storage: Store in a cool and dry place. Keep away from direct sunlight and heat.

Metadata

Product Details

DSLD Entry Date2020-08-23
Product TypeNon-Nutrient/Non-Botanical
FormPowder
DSLD ID232140
Data Updated2026-04-11
Research

Research Evidence

739
Research Sources
47
Avg Quality
472
Clinical Trial
139
Meta Analysis
74
Systematic Review
47
Rct
2
Regulatory Source
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data
Meta Analysis JAMA psychiatry 2021 PubMed DOI
A HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024 PubMed DOI
B Comparison of statins for secondary prevention in patients with ischemic stroke or transient ischemic attack: a systematic review and network meta-analysis
Systematic Review BMC medicine 2019 PubMed DOI
B Efficacy of Creatine Supplementation Combined with Resistance Training on Muscle Strength and Muscle Mass in Older Females: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2021 PubMed DOI
B The Effects of Creatine Supplementation on Upper- and Lower-Body Strength and Power: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2025 PubMed DOI
B Meta-analysis of the efficacy and safety of Finerenone in diabetic kidney disease
Meta Analysis Medicine 2026 PubMed DOI
B Creatine and creatine analogues in hypertension and cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
B HMG CoA reductase inhibitors (statins) for dialysis patients
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.