🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 67% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Vegetarian Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 75mg
📊 5.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 7.5mg UL 100mg
Proprietary Blend
50 mg

Other Ingredients

Microcrystalline Cellulose Capsule Silica

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Suggested Usage:As a dietary supplement, adults take 1 capsule daily or as directed by your health professional.

⚠️ Warnings & Precautions

Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, particularly antidepressants or other psychiatric medications, consult your health professional before use.

Keep out of reach of children.

Use only if safety seal is intact.

🧪 Formulation Notes

Gluten Free, Non-GMO

Brain serotonin precursor

Additional Information

Store in a cool, dry place.

Scan to learn about our manufacturing excellence Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Product Details

UPC / SKU 3 10539 85073 2
DSLD Entry Date 2020-08-23
Product Type Other Combinations
Form Capsule
DSLD ID 232007
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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