L-Carnitine 500 mg by Life Extension — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
100% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 Vegetarian Capsule(s) Serving Size

Non-Nutrient/Non-Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

L-Carnitine

500 mg

📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)

This product: 500mg

Other Ingredients

Vegetable Cellulose Vegetable Stearate Silica

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (88% of products) Nutrient (18% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) capsule on an empty stomach not exceeding four (4) capsules daily, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

🧪 Formulation Notes

Non GMO LE Certified

Helps maintain cellular energy metabolism

Additional Information

Non GMO LE Certified

Store tightly closed in a cool, dry place.

Product Details

UPC / SKU 7 37870 15323 8

DSLD Entry Date 2020-08-23

Product Type Non-Nutrient/Non-Botanical

Form Capsule

Brand Life Extension

DSLD ID 231960

Data Updated 2026-04-11

Research Evidence

80 Research Sources

49 Avg Quality Score

43 Rct

14 Clinical Trial

11 Systematic Review

9 Meta Analysis

2 Regulatory Source

A Propionyl-L-carnitine for intermittent claudication

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI Cochrane

A Carnitine supplements for people with chronic kidney disease requiring dialysis

Systematic Review The Cochrane database of systematic reviews 2022

PubMed DOI Cochrane

A Acetyl-L-carnitine for patients with hepatic encephalopathy

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

B Carnitine for fatigue in multiple sclerosis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B L-carnitine for cognitive enhancement in people without cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

B Carnitine for fatigue in multiple sclerosis

Systematic Review The Cochrane database of systematic reviews 2010

PubMed DOI Cochrane

B Systematic Review and Meta-analysis on Effect of Carnitine, Coenzyme Q10 and Selenium on Pregnancy and Semen Parameters in Couples With Idiopathic Male Infertility

Meta Analysis Urology 2022

PubMed DOI

B Effects of Carnitine and Coenzyme Q10 on Sperm Quality and Pregnancy Rates in Men with Unexplained Infertility: A Systematic Review and Network Meta-Analysis

Systematic Review Reproductive sciences (Thousand Oaks, Calif.) 2025

PubMed DOI

B Efficacy and Effectiveness of Carnitine Supplementation for Cancer-Related Fatigue: A Systematic Literature Review and Meta-Analysis

Meta Analysis Nutrients 2017

PubMed DOI

View all evidence for Carnitine →