Home/ Supplements/ Grape Seed/ Grape Seed Supreme

Grape Seed Supreme

product on market Capsule Designs for Health Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Grape seed and muscadine extracts contain polyphenols and antioxidants that may support cardiovascular health and reduce oxidative stress. Research evidence for these specific effects is generally moderate. These ingredients are typically well-tolerated with a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Grape Seed Supreme
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Botanical
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Grape Extract
200 mg
Market median: 100.0mg (284 products) 10 studies (A:0, B:4)
Muscadine Grape Skin
200 mg

Other Ingredients

Microcrystalline Cellulose Vegetable Stearate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Recommended Use: As a dietary supplement, take two capsules per day with meals, or as directed by your health care practitioner.

Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Formulation Notes

Does not contain gluten.

Additional Information

Notice: Color, size or shape may appear different between lots.

GRS060

MADE WITH NON-GMO INGREDIENTS

STORE IN A COOL, DRY PLACE.

MegaNatural(R)-BP

Guaranteed GMP COMPLIANT Products

For Professional Use Only

Metadata

Product Details

UPC / SKU8 79452 00000 1
DSLD Entry Date2013-09-25
Product TypeBotanical
FormCapsule
BrandDesigns for Health
DSLD ID23196
Data Updated2026-04-11
Research

Research Evidence

14
Research Sources
50
Avg Quality
9
Rct
2
Meta Analysis
2
Clinical Trial
1
Systematic Review
B Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial
Rct Nutrients 2023 PubMed DOI
B Efficacy of Bilberry and Grape Seed Extract Supplement Interventions to Improve Glucose and Cholesterol Metabolism and Blood Pressure in Different Populations-A Systematic Review of the Literature
Systematic Review Nutrients 2021 PubMed DOI
B The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials
Meta Analysis Journal of the American Dietetic Association 2011 PubMed DOI
B The impact of grape seed extract treatment on blood pressure changes: A meta-analysis of 16 randomized controlled trials
Meta Analysis Medicine 2016 PubMed DOI
B Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers
Rct Nutrients 2021 PubMed DOI
C Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial
Rct The British journal of nutrition 2016 PubMed DOI
C Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome
Rct Metabolism: clinical and experimental 2009 PubMed DOI
C Grape seed extract supplementation along with a restricted-calorie diet improves cardiovascular risk factors in obese or overweight adult individuals: A randomized, placebo-controlled trial
Rct Phytotherapy research : PTR 2021 PubMed DOI
C The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function.
Rct European journal of nutrition PubMed DOI
C The effects of grape seed extract supplementation on cardiovascular risk factors, liver enzymes and hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study.
Rct BMC complementary medicine and therapies PubMed DOI
View all evidence for Grape Seed →
Compare

Similar Products

Garlic plus Grape Seed
GNC Herbal Plus · Capsule
100
Grape Seed 100 mg
GNC Nature's Fingerprint · Capsule
100
Grape Seed Extract 50 mg
Nature's Bounty · Capsule
100
Grape Seed Extract 50 mg
Sundown Naturals · Capsule
100
Grape Seed Extract
Vitabase · Capsule
100
View all Grape Seed products →
Grape Seed research Best Grape Seed All Grape Seed products More from Designs for Health View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.