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Milk Thistle 80% Silybin 30%

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100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Silymarin and its active component, silybin, are researched for their potential to support liver health and protect hepatocytes. There is moderate evidence suggesting these compounds may assist in managing certain inflammatory liver conditions. However, overall clinical evidence coverage for these specific effects remains limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle 80% Silybin 30%
Open Full PDF View on NIH DSLD →
Details

Label Data

250 mg
Serving Size
400
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

212 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
78 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

None
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take 250 milligrams (3/32 tsp) a day, or as directed by physician.

Warnings & Precautions

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women.

Consult your physician before use.

Keep out of reach of children.

Formulation Notes

Free of: Sugar, soy, dairy, yeast, gluten, corn and additives.

Additional Information

Derived from Milk thistle Silybum marianum seeds

Storage: Keep dry, cool & dark

US Standard Measuring Spoons Spoon Size (level) milligrams 1/32 teaspoon 83 1/16 teaspoon 166 1/8 teaspoon 333

Metadata

Product Details

DSLD Entry Date2013-06-25
Product TypeNon-Nutrient/Non-Botanical
FormPowder
DSLD ID23177
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.