Silymarin

product on market Powder NOW Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle extract contains silymarin, which is researched for its potential to support liver function and protect hepatocytes. There is moderate evidence suggesting it may assist in managing certain liver conditions. The ingredient profile is generally considered safe for most adults.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Silymarin
Open Full PDF View on NIH DSLD →
Details

Label Data

0.125 tsp
Serving Size
323
Servings
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

None
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: Take 1/8 level teaspoon daily in juice or water, with food. Do not exceed recommended dose.

Warnings & Precautions

Do not exceed recommended dose.

Caution: For adults only.

Not recommended for pregnant/nursing women. Consult physician if taking medication, or have a medical condition especially gall bladder dysfunction).

Keep out of reach of children.

Do not eat freshness packet enclosed.

Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation Notes

Silymarin (Silybum marianum), also known as Milk Thistle, has been used by traditional herbalists for centuries. Scientific studies have indicated that constituents in Silymarin may help to support healthy liver function.

Milk Thistle Extract

Non-GMO

Triangle K

Vegetarian/Vegan

Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients.

Additional Information

Natural color variation may occur in this product. This product is sold by weight not volume.

Supports Liver Function Pure Powder

Non-GMO Triangle K

Botanicals/Herbs Family owned since 1968.

Store in a cool, dry place after opening.

GMP Quality Assured

Metadata

Product Details

UPC / SKU7 33739 04788 5
DSLD Entry Date2019-08-23
Product TypeBotanical
FormPowder
BrandNOW
DSLD ID206176
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
Compare

Similar Products

View all Milk Thistle products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.